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Showing 1-30 of 31 results for "PROBESSIGMA" within Site Content
LightCycler® Probes
LightCycler probes are highly sensitive and sequence-specific fluorescent probes designed for use with the Roche LightCycler instruments.
Dual-Labeled Probes in Digital PCR
Learn more about how digital PCR (dPCR) is used for absolute quantification and for analysis of minority sequences.
OligoEvaluator™ for Tm Calculation & Primer Analysis
We offer an easy-to-use Oligo Analyzer tool, OligoEvaluator™ that provides better primer dimer analysis values for PCR, and serves as an online oligonucleotide sequence calculator and Tm calculator.
No Template Control Oligos (NTCO)
If laboratory handling error has been ruled out, contaminated primers and probes may be to blame for a signal from the qPCR no template control.
Oligonucleotide QA: Quality Management System
QMS features certificates, document control, vendor management, and corrective actions, ensuring quality management standards.
Oligonucleotide Label Licenses
Label licenses for our oligonucleotide products, including Black Hole Quencher®, BlackBerry® Quencher, and Locked Nucleic Acid (LNA®).
OligoArchitect™ Consultative
For more complex and demanding applications, utilize our consultative service to ensure the success of your assay.
Custom Oligo Blanket Orders
Custom oligo Blanket Purchase Order tracking system simplifies expenditure management for customers.
Oligonucleotide Purification
Learn about the importance of oligonucleotide purification, recommended methods, common techniques and applications, and key steps in the processes.
Custom siRNA Duplex Plates
Use our synthetic, small interfering RNA (siRNA) duplex plates to identify gene function, elucidate pathways, and screen for potential new drug targets.
WellRED Oligos
WellRED oligos use cyanine-based fluorescent dyes with high extinction coefficients that absorb in the near-infrared region, thereby reducing background noise from biological materials, resulting in highly sensitive detection.
Custom RNA Oligos
RNA Oligo Specifications, Shipping Schedule, Minimum Yield Guarantees, Quality Control, Quality Assurance
LightCycler® Probes
LightCycler probes are highly sensitive and sequence-specific fluorescent probes designed for use with the Roche LightCycler instruments.
Custom cGMP Oligos Coming in 2023
If you commercialize Molecular Diagnostics (MDx), develop Laboratory Developed Tests (LDTs), or conduct preclinical research on therapeutics, then your final kit, assay, or modality must have an extraordinary level of quality to comply with strict regulatory or study standards.
Custom Oligos for Commercial Use
As the world’s leading supplier of oligonucleotides, Sigma-Aldrich delivers the largest portfolio of expertise to its diagnostic partners. ISO 13485 & cGMP/ASR certified.
Custom cGMP Oligos
If you commercialize Molecular Diagnostics (MDx), develop Laboratory Developed Tests (LDTs), or conduct preclinical research on therapeutics, then your final kit, assay, or modality must have an extraordinary level of quality to comply with strict regulatory or study standards.
Custom Next-Gen Sequencing Oligos
Regardless of next-generation sequencing (NGS) platform, universal and index adapter sequences are required for the proper assembly of sample fragments.
Dual-Labeled Probes
Dual-Labeled Probes are the most common probe type for qPCR and are often referred to as hydrolysis probes.
Molecular Beacons
Learn about precision Sigma-Aldrich Molecular Beacon oligonucleotide probes used for sequence detection in qPCR for in vitro research.
Positive Control siRNA
MISSION Positive Control siRNA, validated for siRNA silencing experiments, saves time in gene silencing research.
Custom siRNA
RNA interference via siRNA offers precise gene silencing, aiding gene function studies and drug target screening.
Scorpions® Probes
Scorpions probes are highly sensitive, sequence-specific, bi-labeled fluorescent probe/primer hybrids designed for qPCR.
Custom DNA Oligos: Standard DNA Synthesis
High-quality custom DNA oligos made to meet your specifications (scale, purification, length, dry/solution, modifications, tubes/plates).
DNA and siRNA Custom iScale Oligos™
Learn about our precision manufacturing capabilities for scalable amounts of custom DNA and siRNA oligos for research, diagnostics, and therapeutics
Predesigned siRNA
Rosetta siRNA Design Algorithm optimizes siRNA sequences for reduced off-target effects and increased RNAi performance.
Fast siRNA
We can quickly synthesize and ship custom siRNA using your sequences.
Easy Oligo
Easy Oligo is suitable for a wide range of applications including PCR , sequencing and real-time quantitative PCR (as a primer)
Long Oligos
Techniques for long oligo synthesis and purification offer superior quality unmatched by other suppliers.
Pure & Simple Primers
Oligo synthesis technology delivers high-quality products for research applications with full-length purity.
Locked Nucleic Acid & Minor Groove Binder / Eclipse Dark Quencher
Explore Locked Nucleic Acid and MGB. These oligo modifications offer stability and specificity in molecular analysis, making them ideal for research and diagnostic applications.
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