Showing 1-23 of 23 results for "R6148"
Seasonal changes in broodstock spawning performance and egg quality in ballan wrasse (Labrus bergylta)
Grant B, et al.
Aquaculture (Amsterdam, Netherlands), 464(, 505-514 (2016)
Alberto Pérez-Posada et al.
PLoS genetics, 16(3), e1008584-e1008584 (2020-03-17)
Progression through the cell cycle in eukaryotes is regulated on multiple levels. The main driver of the cell cycle progression is the periodic activity of cyclin-dependent kinase (CDK) complexes. In parallel, transcription during the cell cycle is regulated by a...
Carla Burrows et al.
Nucleic acids research, 38(16), 5542-5553 (2010-05-01)
The RNA binding protein Larp1 was originally shown to be involved in spermatogenesis, embryogenesis and cell-cycle progression in Drosophila. Our data show that mammalian Larp1 is found in a complex with poly A binding protein and eukaryote initiation factor 4E...
Danny E Miller et al.
G3 (Bethesda, Md.), 10(11), 4271-4285 (2020-09-26)
Balancers are rearranged chromosomes used in Drosophila melanogaster to maintain deleterious mutations in stable populations, preserve sets of linked genetic elements and construct complex experimental stocks. Here, we assess the phenotypes associated with breakpoint-induced mutations on commonly used third chromosome...
Taotao Shou et al.
Molecular medicine reports, 19(2), 1049-1055 (2018-11-30)
MicroRNAs (miRNAs) are acknowledged as essential regulators in human cancer types, including glioblastoma (GBM). However, the functions of microRNA‑3666 (miR‑3666) in GBM remain unclear. In the present study, it was identified that the expression of miR‑3666 was significantly downregulated in...
Yang Liu et al.
Pathology, research and practice, 215(12), 152641-152641 (2019-11-16)
Retinoblastoma (RB) is the most common primary intraocular malignancy in children. Accumulating evidences have clarified that microRNAs (miRNAs) modulated signaling molecules by acting as oncogenes or tumor-suppressor genes in RB. Thus, in our study, we aimed to investigate the function...
Catherine R Back et al.
Marine drugs, 19(2) (2021-03-07)
To tackle the growing problem of antibiotic resistance, it is essential to identify new bioactive compounds that are effective against resistant microbes and safe to use. Natural products and their derivatives are, and will continue to be, an important source...
MicroRNA-3666 suppresses the growth and migration of glioblastoma cells by targeting KDM2A
Shou T, et al.
Molecular Medicine Reports, 19(2), 1049-1055 (2019)
Kimberly M Brothers et al.
Scientific reports, 5, 14003-14003 (2015-09-15)
The epithelium provides a crucial barrier to infection, and its integrity requires efficient wound healing. Bacterial cells and secretomes from a subset of tested species of bacteria inhibited human and porcine corneal epithelial cell migration in vitro and ex vivo....
Nimesulide inhibits proliferation and induces apoptosis of pancreatic cancer cells by enhancing expression of PTEN
Chu M, et al.
Experimental and Therapeutic Medicine, 16(1), 370-376 (2018)
Serap Erkek et al.
Cancer cell, 35(1), 95-110 (2019-01-01)
Biallelic inactivation of SMARCB1, encoding a member of the SWI/SNF chromatin remodeling complex, is the hallmark genetic aberration of atypical teratoid rhabdoid tumors (ATRT). Here, we report how loss of SMARCB1 affects the epigenome in these tumors. Using chromatin immunoprecipitation...
Kevin P Foley et al.
Molecular metabolism, 42, 101067-101067 (2020-08-30)
Hyperinsulinemia can be both a cause and consequence of obesity and insulin resistance. Hyperinsulinemia can result from increased insulin secretion and/or reduced insulin clearance. While many studies have focused on mechanisms triggering insulin secretion during obesity, the triggers for changes...
Erika Terzuoli et al.
Oncotarget, 8(47), 83207-83224 (2017-11-16)
Hydroxytyrosol (HT), a polyphenol of olive oil, downregulates epidermal growth factor (EGFR) expression and inhibits cell proliferation in colon cancer (CC) cells, with mechanisms similar to that activated by the EGFR inhibitor, cetuximab. Here, we studied whether HT treatment would...
Phenotypic plasticity and biogeographic variation in physiology of habitat-forming seaweed: response to temperature and nitrate
Flukes EB, et al.
Journal of Phycology, 51(5), 896-909 (2015)
Kevin P Foley et al.
Nature communications, 9(1), 4681-4681 (2018-11-10)
The intestinal microbiota and insulin sensitivity are rapidly altered after ingestion of obesogenic diets. We find that changes in the composition of the fecal microbiota precede changes in glucose tolerance when mice are fed obesogenic, low fiber, high fat diets...
Abdou ElSharawy et al.
Oncotarget, 7(46), 75353-75365 (2016-09-30)
The emerging potential of miRNAs as biomarkers for cancer detection demands parallel evaluation of strategies for reliable identification of disease-related signatures from easily accessible and pertinent body compartments. Here, we addressed whether efficient concentration of circulating miRNA-carrying particles is a...
Lenka Senohrabkova et al.
Current genetics, 65(4), 919-940 (2019-02-05)
Cells have elaborated a complex strategy to maintain protein homeostasis under physiological as well as stress conditions with the aim to ensure the smooth functioning of vital processes and producing healthy offspring. Impairment of one of the most important processes...
Shiwen Zhang et al.
International journal of nanomedicine, 9, 1931-1946 (2014-05-03)
Gold nanorods (AuNRs) have been used in plasmonic photothermal therapy (PPTT), which is thought to be more efficient and selective than conventional photothermal therapy. The efficiency and safety of PPTT can be improved by functionally modifying the gold nanorods with...
Neha Nagpal et al.
Cell stem cell, 26(6), 896-909 (2020-04-23)
Genetic lesions that reduce telomerase activity inhibit stem cell replication and cause a range of incurable diseases, including dyskeratosis congenita (DC) and pulmonary fibrosis (PF). Modalities to restore telomerase in stem cells throughout the body remain unclear. Here, we describe...
Wei Cai et al.
Experimental and therapeutic medicine, 17(5), 3781-3788 (2019-04-17)
miR-552 promotes tumor growth and metastasis in colorectal cancer. However, the function of miR-552 in osteosarcoma remains unclear. The current study investigated the role and mechanism of miR-552-5p in the proliferation, migration and invasion of osteosarcoma cells. miR-552-5p was significantly...
Alessia Garufi et al.
Biomolecules, 10(3) (2020-03-07)
The unfolded protein response (UPR) is an adaptive response to intrinsic and external stressors, and it is mainly activated by the accumulation of misfolded proteins at the endoplasmic reticulum (ER) lumen producing ER stress. The UPR signaling network is interconnected...
Determination of the presence of 5-methylcytosine in Paramecium tetraurelia
Singh A, et al.
PloS one, 13(10), e0206667-e0206667 (2018)

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