Thrombosis and haemostasis, 80(3), 428-436 (1998-10-06)
We recently reported that washed platelets (WP) activated with ADP and expressing surface-bound vWF aggregated in flow through small tubes or in a cylindrical couette device at physiological shear rates of G = 300 s(-1)-1000 s(-1) in the absence of...
Antimicrobial agents and chemotherapy, 58(10), 6185-6196 (2014-08-13)
The emergence of antibiotic-resistant pathogenic bacteria within the last decades is one reason for the urgent need for new antibacterial agents. A strategy to discover new anti-infective compounds is the evaluation of the genetic capacity of secondary metabolite producers and...
Species variability in platelet aggregation response to different agonists
Pelagalli A, et al.
Journal of Comparative Pathology, 127(2-3), 126-132 (2019)
Biochemical and biophysical research communications, 261(3), 784-789 (1999-08-12)
Platelet glycoprotein (GP) Ib/IX/V complex is a receptor for von Willebrand factor (vWf), which plays a crucial role in primary hemostasis by mediating platelet adhesion to injured blood vessels. We have expressed in CHO cells a fragment of GPIba that...
American journal of kidney diseases : the official journal of the National Kidney Foundation, 32(1), 132-138 (1998-07-21)
A bleeding diathesis caused by platelet dysfunction is a major cause of morbidity and mortality in patients with uremia. Platelet adhesion to vascular subendothelium is defective in uremia and depends on the interactions of the platelet glycoprotein (GP) Ib/IX complex...
Novel antibodies against GPIb alpha inhibit pulmonary metastasis by affecting vWF-GPIb alpha interaction
Qi Y, et al.
Journal of Hematology & Oncology, 11(1), 117-117 (2018)
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