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The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1.
Oberlin E, et al.
Nature, 382(6594), 833-835 (1996)
The diagnostic and prognostic value of serum CXCL12 levels in patients with ischemic stroke
Duan XX, et al.
Neurological Sciences, 36, 2227-2234 (2015)
Discovery of Small Molecule CXCR4 Antagonists
Zhan W, et al.
Journal of Medicinal Chemistry, 50, 5655-5664 (2007)
Wnt/?-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cells
International Journal of Clinical and Experimental Pathology, 8(10), 12357?12367-12357?12367 (2015)
The diagnostic and prognostic value of serum CXCL12 levels in patients with ischemic stroke.
Duan XX
Neurological Sciences, 36, 2227-2234 (2015)
M Shirozu et al.
Genomics, 28(3), 495-500 (1995-08-10)
Stromal cell-derived factors 1 alpha and 1 beta are small cytokines belonging to the intercrine CXC subfamily and originally isolated from a murine bone-marrow stroma cell line by the signal sequence trap method. cDNA and genomic clones of human SDF1...
SDF-1/CXCR4 expression is an independent negative prognostic biomarker in patients with head and neck cancer after primary radiochemotherapy
Colle CD, et al.
Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology, 126, 125-131 (2018)
K Tashiro et al.
Science (New York, N.Y.), 261(5121), 600-603 (1993-07-30)
A method was developed to clone, without the use of specific functional assays, complementary DNAs (cDNAs) that carry specific amino-terminal signal sequences, such as those encoding intercellular signal-transducing molecules and receptors. The vector used in this system directed the cell...
C C Bleul et al.
Nature, 382(6594), 829-833 (1996-08-29)
Chemokines are chemotactic cytokines that activate and direct the migration of leukocytes. There are two subfamilies, the CXC and the CC chemokines. We recently found that the CXC-chemokine stromal cell-derived factor-1 (SDF-1) is a highly efficacious lymphocyte chemoattractant. Chemokines act...
Chemokines in multiple myeloma
Aggarwal R, et al.
Experimental Hematology, 34(10), 1289?-12295 (2006)
Diversity and inter-connections in the CXCR4 chemokine receptor/ligand family: molecular perspectives
Pawig L, et al.
Frontiers in Immunology (2015)
Structure and Chromosomal Localization of the Human Stromal Cell-Derived Factor 1 (SDF1) Gene
Shirozu M, et al.
Genomics, 28, 495-500 (1995)
The α-Chemokine, Stromal Cell-derived Factor-1α, Binds to the
Transmembrane G-protein-coupled CXCR-4 Receptor and
Activates Multiple Signal Transduction Pathways.
Ganju RK, et al.
The Journal of Biological Chemistry, 273, 23169?- 233175 (1998)
T Nagasawa et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(6), 2305-2309 (1994-03-15)
Generation and proliferation of early B-cell progenitors have been known to require stromal cell-derived molecules. A stromal cell line, PA6, was found to produce a soluble mediator, which was distinct from interleukin 7 (IL-7) and stem cell factor and supported...
E Oberlin et al.
Nature, 382(6594), 833-835 (1996-08-29)
A putative chemokine receptor that we previously cloned and termed LESTR has recently been shown to function as a co-receptor (termed fusin) for lymphocyte-tropic HIV-1 strains. Cells expressing CD4 became permissive to infection with T-cell-line-adapted HIV-1 strains of the syncytium-inducing...