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Showing 1-17 of 17 results for "s2177" within Papers
Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss
Tiwari SS, et al.
Brain, 139(10), 2751-2751 (2016)
Synaptotagmin in Ca2+dependent exocytosis: dynamic action in a flash
Tokuoka H and Goda Y
Neuron, 38(4), 521-524 (2003)
The C2B domain of synaptotagmin is a Ca2+ sensing module essential for exocytosis
Desai RC, et al.
The Journal of Cell Biology, 150(5), 1125-1136 (2000)
Scott W Messenger et al.
American journal of physiology. Gastrointestinal and liver physiology, 305(6), G439-G452 (2013-07-23)
Zymogen granule (ZG) formation in acinar cells involves zymogen cargo sorting from trans-Golgi into immature secretory granules (ISGs). ISG maturation progresses by removal of lysosomal membrane and select content proteins, which enter endosomal intermediates prior to their apical exocytosis. Constitutive
Zhe-Zhe Zhang et al.
Frontiers in aging neuroscience, 12, 157-157 (2020-08-11)
Age-associated impairment of spatial learning and memory (AISLM) presents substantial challenges to our health and society. Increasing evidence has indicated that embryonic exposure to inflammation accelerates the AISLM, and this can be attributable, at least partly, to changed synaptic plasticity
The C2 domains of synaptotagmin-partners in exocytosis
Bai J and Chapman ER
Trends in Biochemical Sciences, 29(3), 143-151 (2004)
Scott W Messenger et al.
The Journal of biological chemistry, 289(40), 28040-28053 (2014-08-21)
Acinar cell zymogen granules (ZG) express 2 isoforms of the vesicle-associated membrane protein family (VAMP2 and -8) thought to regulate exocytosis. Expression of tetanus toxin to cleave VAMP2 in VAMP8 knock-out (-/-) acini confirmed that VAMP2 and -8 are the
Anuttama Kulkarni et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(3), 965-974 (2016-12-07)
Acetylcholinesterase (AChE), which is implicated in the pathophysiology of neurological disorders, is distributed along the axon and enriched at the presynaptic basal lamina. It hydrolyses the neurotransmitter acetylcholine, which inhibits synaptic transmission. Aberrant AChE activity and ectopic axonal accumulation of
Tumor protein D52 controls trafficking of an apical endolysosomal secretory pathway in pancreatic acinar cells
Messenger SW, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 305(6), G439-G452 (2013)
The products of the Drosophila stoned locus interact with synaptic vesicles via synaptotagmin
Phillips AM, et al.
The Journal of Neuroscience, 20(22), 8254-8261 (2000)
Chia-Chang Tsai et al.
The journal of physical chemistry. B, 112(30), 9165-9173 (2008-07-05)
Exocytosis of a single bovine adrenal chromaffin cell, triggered by histamine stimulation, was investigated via the electric responses detected with single-walled carbon-nanotube field-effect transistors (SWCNT-FET) and the morphological changes acquired by atomic force microscopy (AFM). Secretion of chromogranin A (CgA)
Anshua Ghosh et al.
Translational psychiatry, 10(1), 192-192 (2020-06-18)
Alzheimer's disease (AD) is characterised by Aβ and tau pathology as well as synaptic degeneration, which correlates best with cognitive impairment. Previous work suggested that this pathological complexity may result from changes in mRNA translation. Here, we studied whether mRNA
Zhe-Zhe Zhang et al.
Neural plasticity, 2022, 1483101-1483101 (2022-05-17)
A mounting body of evidence suggests that prenatal inflammation may enhance the rate of age-associated cognitive decline and may involve aberrant amounts of synaptic proteins in the hippocampus, including synaptotagmin-1 (Syt1) and activity-regulated cytoskeleton-associated protein (Arc). However, little is known
M Peters et al.
Genes, brain, and behavior, 8(3), 320-329 (2009-02-05)
We injected small interfering RNAs (siRNAs) directly into the hippocampus of wild-type mice, knocking down expression of cyclic AMP responsive element-binding protein (CREB) and disrupting long-term, but not short-term, memory after both contextual and trace fear conditioning. In contrast, similar
Expression, localization, and functional role for synaptotagmins in pancreatic acinar cells
Falkowski MA, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 301(2), G306-G316 (2011)
Sachin Suresh Tiwari et al.
Brain : a journal of neurology, 139(Pt 10), 2751-2765 (2016-08-16)
Characteristic features of Alzheimer's disease are memory loss, plaques resulting from abnormal processing of amyloid precursor protein (APP), and presence of neurofibrillary tangles and dystrophic neurites containing hyperphosphorylated tau. Currently, it is not known what links these abnormalities together. Cytoplasmic
Daichi G Suzuki et al.
The Journal of comparative neurology, 523(2), 251-261 (2014-09-23)
Vertebrates are equipped with so-called camera eyes, which provide them with image-forming vision. Vertebrate image-forming vision evolved independently from that of other animals and is regarded as a key innovation for enhancing predatory ability and ecological success. Evolutionary changes in
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