sab4200283

" within Papers

Tensin is potentially involved in extracellular matrix production in mesangial cells.

Yamashita M

Histochemistry and Cell Biology, 121, 245-254 (2004)

Mechano-responsiveness of fibrillar adhesions on stiffness-gradient gels.

Nuria Barber-Pérez et al.

Journal of cell science, 133(12) (2020-05-13)

Fibrillar adhesions are important structural and adhesive components in fibroblasts, and are required for fibronectin fibrillogenesis. While nascent and focal adhesions are known to respond to mechanical cues, the mechanoresponsive nature of fibrillar adhesions remains unclear. Here, we used ratiometric

Genetic association analyses highlight biological pathways underlying mitral valve prolapse

Dina C

Nature Genetics, 47, 1206?1211-1206?1211 (2015)

Tensin

Lo S H

The International Journal of Biochemistry & Cell Biology, 36(1), 31-34 (2004)

AMPK negatively regulates tensin-dependent integrin activity.

Maria Georgiadou et al.

The Journal of cell biology, 216(4), 1107-1121 (2017-03-16)

Tight regulation of integrin activity is paramount for dynamic cellular functions such as cell matrix adhesion and mechanotransduction. Integrin activation is achieved through intracellular interactions at the integrin cytoplasmic tails and through integrin-ligand binding. In this study, we identify the

Filamin A mediates isotropic distribution of applied force across the actin network.

Abhishek Kumar et al.

The Journal of cell biology, 218(8), 2481-2491 (2019-07-19)

Cell sensing of externally applied mechanical strain through integrin-mediated adhesions is critical in development and physiology of muscle, lung, tendon, and arteries, among others. We examined the effects of strain on force transmission through the essential cytoskeletal linker talin. Using

Tensin can induce JNK and p38 activation.

Katz BZ

Biochemical and Biophysical Research Communications, 272, 717-720 (2000)

Tensin 1 Is Essential for Myofibroblast Differentiation and Extracellular Matrix Formation.

Bernau K

American Journal of Respiratory Cell and Molecular Biology, 56, 465-476 (2017)

Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity.

Abhishek Kumar et al.

The Journal of cell biology, 213(3), 371-383 (2016-05-11)

Integrin-dependent adhesions are mechanosensitive structures in which talin mediates a linkage to actin filaments either directly or indirectly by recruiting vinculin. Here, we report the development and validation of a talin tension sensor. We find that talin in focal adhesions

Page 1 of 1