sab4502010

" within Papers

Superoxide generation from nNOS splice variants and its potential involvement in redox signal regulation.

Hideshi Ihara et al.

The Biochemical journal, 474(7), 1149-1162 (2017-01-28)

We previously demonstrated different spacial expression profiles of the neuronal nitric oxide (NO) synthase (nNOS) splice variants nNOS-µ and nNOS-α in the brain; however, their exact functions are not fully understood. Here, we used electron paramagnetic resonance to compare the

Role of Nitric Oxide in Stress-Induced Anxiety: From Pathophysiology to Therapeutic Target.

A Kumar et al.

Vitamins and hormones, 103, 147-167 (2017-01-08)

Stress is often marked by a state of hyperarousal to aid the initiation of necessary stress response for the successful management of stressful stimuli. It can be manifested as a challenge (stimulus) that requires behavioral, psychological, and physiological adaptations for

Epigenetic modifications of Dexras 1 along the nNOS pathway in an animal model of multiple sclerosis.

G Catanzaro et al.

Journal of neuroimmunology, 294, 32-40 (2016-05-04)

The development of multiple sclerosis, a major neurodegenerative disease, is due to both genetic and environmental factors that might trigger aberrant epigenetic changes of the genome. In this study, we analysed global DNA methylation in the brain of mice upon

Distinct downstream signaling and the roles of VEGF and PlGF in high glucose-mediated injuries of human retinal endothelial cells in culture.

Wanzhen Jiao et al.

Scientific reports, 9(1), 15339-15339 (2019-10-28)

Vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) plays a crucial role in breakdown of the blood-retinal barrier due to hyperpermeability in diabetic retinopathy (DR). However, the distinct signaling driven by VEGF and PlGF in the pathogenesis of

Early and Delayed Impact of Nanosilver on the Glutamatergic NMDA Receptor Complex in Immature Rat Brain.

Beata Dąbrowska-Bouta et al.

International journal of molecular sciences, 22(6) (2021-04-04)

Silver nanoparticles (AgNPs) are the one of the most extensively used nanomaterials. The strong antimicrobial properties of AgNPs have led to their use in a wide range of medical and consumer products. Although the neurotoxicity of AgNPs has been confirmed

Genome-wide linkage analysis in families with infantile hypertrophic pyloric stenosis indicates novel susceptibility loci.

Anna Svenningsson et al.

Journal of human genetics, 57(2), 115-121 (2011-12-14)

Infantile hypertrophic pyloric stenosis (IHPS) is a common cause of upper gastrointestinal obstruction during infancy. A multifactorial background of the disease is well established. Multiple susceptibility loci including the neuronal nitric oxide synthase (NOS1) gene have previously been linked to

The human coronary vasodilatory response to acute mental stress is mediated by neuronal nitric oxide synthase.

Sitara G Khan et al.

American journal of physiology. Heart and circulatory physiology, 313(3), H578-H583 (2017-06-25)

Mental stress-induced ischemia approximately doubles the risk of cardiac events in patients with coronary artery disease, yet the mechanisms underlying changes in coronary blood flow in response to mental stress are poorly characterized. Neuronal nitric oxide synthase (nNOS) regulates basal

Role of nitric oxide synthase in the development of bone cancer pain and effect of L-NMMA.

Yan Yang et al.

Molecular medicine reports, 13(2), 1220-1226 (2015-12-10)

Spinal nitric oxide is involved in the mechanisms of pain generation and transmission during inflammatory and neuropathic pain. The aim of the present study was to explore the role of spinal nitric oxide in the development of bone cancer pain.

Page 1 of 1