Showing 1-10 of 10 results for "SRP3124"
M Saarma
Trends in neurosciences, 24(8), 427-429 (2001-07-31)
Glial cell line-derived neurotrophic factor (GDNF) family ligands (GFL) are potent survival factors and regulators for central and peripheral neurons. GFLs bind to specific glycosyl phosphatidylinositol (GPI)-anchored co-receptors (GFRalpha1-alpha4), but signal through a common c-Ret receptor. Both GPI-anchored and soluble...
R H Baloh et al.
Neuron, 21(6), 1291-1302 (1999-01-12)
The glial cell line-derived neurotrophic factor (GDNF) ligands (GDNF, Neurturin [NTN], and Persephin [PSP]) signal through a multicomponent receptor system composed of a high-affinity binding component (GFRalpha1-GFRalpha4) and a common signaling component (RET). Here, we report the identification of Artemin...
Novel functions and signalling pathways for GDNF
Hannu Sariola and Mart Saarma
Journal of Cell Science. Supplement, 116 (2003)
Hendrik Lehnert
Pathophysiology of Haemostasis and Thrombosis (2004)
David Bliman et al.
Scientific reports, 5, 13109-13109 (2015-08-25)
Proto-oncogene tyrosine-protein kinase receptor RET is implicated in the development and maintenance of neurons of the central and peripheral nervous systems. Attaching activity-compromising photocleavable groups (caging) to inhibitors could allow for external spatiotemporally controlled inhibition using light, potentially providing novel...
P T Kotzbauer et al.
Nature, 384(6608), 467-470 (1996-12-05)
The normal development of the vertebrate nervous system entails the death of 30-70% of the neurons originally generated in most neuronal populations. This naturally occurring cell death is regulated by specific neurotrophic factors that promote neuronal survival and which are...
Neurturin has multiple neurotrophic effects on adult rat sacral parasympathetic ganglion neurons.
Yewlan Wanigasekara and Janet R Keast
The European Journal of Neuroscience, 22 (2005)
Hyun-Jung Park et al.
Molecular endocrinology (Baltimore, Md.), 29(2), 289-306 (2014-12-31)
Glial cell line-derived neurotrophic factor (GDNF) is a TGFβ family member, and GDNF signals through a glycosyl-phosphatidylinositol-linked cell surface receptor (GFRα1) and RET receptor tyrosine kinase. GDNF signaling plays crucial roles in urogenital processes, ranging from cell fate decisions in...
Neurotrophic factors and their effects in the treatment of multiple sclerosis
Shahnaz R
Advanced Biomedical Research (2015)
Neurturin is a neurotrophic factor for penile parasympathetic neurons in adult rat
Journal of Neurobiology, 43 (2000)

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