Showing 1-8 of 8 results for "SRP3227"
E Minina et al.
Development (Cambridge, England), 128(22), 4523-4534 (2001-11-21)
During endochondral ossification, two secreted signals, Indian hedgehog (Ihh) and parathyroid hormone-related protein (PTHrP), have been shown to form a negative feedback loop regulating the onset of hypertrophic differentiation of chondrocytes. Bone morphogenetic proteins (BMPs), another family of secreted factors...
Riccardo Sangermano et al.
Ophthalmology, 123(6), 1375-1385 (2016-03-16)
To elucidate the functional effect of the ABCA4 variant c.5461-10T→C, one of the most frequent variants associated with Stargardt disease (STGD1). Case series. Seventeen persons with STGD1 carrying ABCA4 variants and 1 control participant. Haplotype analysis of 4 homozygotes and...
Noggin antagonizes BMP signaling to create a niche for adult neurogenesis.
Lim DA, et al.
Neuron, 28(3), 713-726 (2000)
Bruce A Corliss et al.
Investigative ophthalmology & visual science, 60(15), 5095-5103 (2019-12-12)
To establish Myh11 as a marker of a subset of corneal endothelial cells (CECs), and to demonstrate the feasibility of restoring the corneal endothelium with Myh11-lineage (Myh11-Lin[+]) adipose-derived stromal cells (ASCs). Intraperitoneal administration of tamoxifen and (Z)-4-hydroxytamoxifen eyedrops were used...
Conditional inactivation of noggin in the postnatal skeleton causes osteopenia.
Canalis E, et al.
Endocrinology, 153(4), 1616-1626 (2012)
Yong-Guo Zhang et al.
Autophagy, 15(11), 1935-1953 (2019-03-22)
Extracellular HMGB1 (high mobility group box 1) is considered as a damage-associated molecular pattern protein. However, little is known about its intracellular role. We studied the mechanism whereby intestinal epithelial HMGB1 contributes to host defense, using cell culture, colonoids, conditional...
L J Brunet et al.
Science (New York, N.Y.), 280(5368), 1455-1457 (1998-06-20)
Noggin is a bone morphogenetic protein (BMP) antagonist expressed in Spemann's organizer. Murine Noggin is expressed in condensing cartilage and immature chondrocytes, as are many BMPs. In mice lacking Noggin, cartilage condensations initiated normally but developed hyperplasia, and initiation of...
The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4.
Zimmerman LB, et al.
Cell, 86(4), 599-606 (1996)

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