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ATRP: Complete Tools for the Synthesis of Well-Defined, Functionalized Polymers
Find how atom transfer radical polymerization (ATRP) tools can be used for the synthesis of well-defined functionalized polymers.
ATRP Ligands and Initiators for the Clean Synthesis of Functional Polymers
Atom transfer radical polymerization (ATRP) has emerged as one of the most successful synthetic techniques for the preparation of polymers with predetermined molecular weights, narrow molecular weight distributions, and high degrees of chain end functionalities.
Verkade S Bases
Strong and Hindered Bases in Organic Synthesis
Solubility Enhancement of Poorly Water Soluble Molecules Using Dendrimers
Environmental concerns are driving the replacement of volatile organic solvents by water and aqueous mixtures. This change often creates challenges because many organic molecules show low water solubility.
Peptide Stability and Potential Degradation Pathways
To prevent or minimize peptide degradation we recommend storing the peptide in lyophilized form at –20 °C or –80 °C. Once in solution, the peptide/protein should be stored frozen in individual aliquots to avoid freeze-thaw cycles. Also, prolonged exposure to
Fluorinating Reagents
The importance of selectively fluorinating compounds in medicinal chemistry, biology, and organic synthesis is well appreciated and provides a major impetus to the discovery of new and mild fluorinating agents that can operate safely and efficiently.
Click Chemistry in Drug Discovery
Drug discovery process by utilizing chemistry reaction of Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition of terminal alkynes with organoazides to yield 1,4-disubstituted 1,2,3-triazoles.
Click Chemistry in Drug Discovery
Drug discovery process by utilizing chemistry reaction of Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition of terminal alkynes with organoazides to yield 1,4-disubstituted 1,2,3-triazoles.
Palladacycle Coupling Catalysts
Palladacyclic catalysts developed by Bedford’s group are examples of a select group of catalysts capable of affecting a variety of coupling reactions using difficult to activate aryl chlorides at very low catalyst loadings.
Click Chemistry
Click Chemistry a newer approach to the synthesis of drug-like molecules that can accelerate the drug discovery process by utilizing a few practical and reliable reactions.
Traditional Strong and Hindered Bases
Functionalization of Fluorescent Nanodiamonds for Bioimaging
Properties & characteristics of Fluorescent Nanodiamonds & biofunctionalization strategies explained. Conjugation protocols for streptavidin functionalization, biotinylation & coupling biotinylated/streptavidin provided. FNDs may be used for labeling of low-level expressed targets, Bioimaging & Bioconjugation.
Molecular Monolayers on Silicon Surfaces
This article briefly reviews the methods and mechanisms for the formation of molecular monolayers on silicon surfaces, the properties of these monolayers and current perspectives regarding their application in molecular electronic and sensing applications.
The Potential of Dendritic Polyester Scaffolds as Biocompatible Drug Delivery Agents
Professor Michael Malkoch provides an overview of the unique properties of dendritic molecules and their application in biomedical fields. He highlights bis-MPA dendritic scaffolds as a promising biodegradable and biocompatible platform for drug delivery applications
Hydrosilylation Catalyst
This robust protocol for hydrosilylation of terminal acetylenes to give α-vinylsilanes using [Cp*Ru(MeCN)3]PF6, as well as a number of other catalysts for hydrosilylation, comes from the Trost group at Stanford University.
Reproducibility with Biological Buffers
Biological buffers are organic substances that maintain a constant pH over a given range by neutralizing the effects of hydrogen ions.
Metal-Organic Frameworks in Sustainable Energy Technologies
Metal-organic frameworks, a subset of coordination polymers, represent a powerful new tool for a plethora of alternative energy applications. MOFs are readily available using simple synthetic strategies that supply tailored, high surface area materials.
Alkyne Hydrosilylation
Vinyl-metal reagents play a pivotal role in organic synthesis. Among the vinyl-metal reagents available, silicon-based reagents are of increasing importance. This is largely due to their low cost, minimal toxicity, ease of handling, and the simplicity of byproduct removal.
Atto Dyes for Superior Fluorescent Imaging
Atto dyes are a series of fluorescent dyes that meet the critical needs of modern fluorescent technologies.
Silicon Nitride Atomic Layer Deposition: A Brief Review of Precursor Chemistry
atomic layer deposition (ALD), microelectronics, Mo:Al2O3 films, nanocomposite coating, photovoltaics, semiconductor devices, W:Al2O3 films, composite films, layer-by-layer
Organic and Hybrid Electronics in Optical Analytical Applications
Professor Shinar (Iowa State University, USA) summarizes the developments of a variety of sensor configurations based on organic and hybrid electronics, as low-cost, disposable, non-invasive, wearable bioelectronics for healthcare.