Showing 1-30 of 56 results for "V001661"
Rachel Parke-Houben et al.
Journal of materials science. Materials in medicine, 26(2), 107-107 (2015-02-11)
Three-dimensional scaffolds based on inverted colloidal crystals (ICCs) were fabricated from sequentially polymerized interpenetrating polymer network (IPN) hydrogels of poly(ethyleneglycol) and poly(acrylic acid). This high-strength, high-water-content IPN hydrogel may be suitable for use in an artificial cornea application. Development of...
Seyedsina Moeinzadeh et al.
Tissue engineering. Part A, 21(1-2), 134-146 (2014-07-23)
An attractive approach to reduce the undesired side effects of bone morphogenetic proteins (BMPs) in regenerative medicine is to use osteoinductive peptide sequences derived from BMPs. Although the structure and function of BMPs have been studied extensively, there is limited...
Vincenzo Taresco et al.
The journal of physical chemistry. B, 119(26), 8369-8379 (2015-06-16)
Amphiphilic polyelectrolytes (APEs), exhibiting particular self-association properties in aqueous media, can be used in different industrial applications, including drug delivery systems. Their typical core-shell structure (micelle) depends on the balance of interactions between hydrophobic and ionizable monomer units. In this...
Chariya Kaewsaneha et al.
ACS applied materials & interfaces, 7(42), 23373-23386 (2015-10-07)
Fluorescent-magnetic particles (FMPs) play important roles in modern materials, especially as nanoscale devices in the biomedical field. The interesting features of FMPs are attributed to their dual detection ability, i.e., fluorescent and magnetic modes. Functionalization of FMPs can be performed...
Acrylic acid.
IARC monographs on the evaluation of carcinogenic risks to humans, 71 Pt 3, 1223-1230 (1999-09-07)
Krassimira Yoncheva et al.
International journal of pharmaceutics, 486(1-2), 259-267 (2015-04-04)
The potential of poly(methyl methacrylate-co-acrylic acid) (PMMA-AA) copolymers to form hollow particles and their further formulation as curcumin delivery system have been explored. The particles were functionalized by crosslinking the acrylic acid groups via bis-amide formation with either cystamine (CYS)...
Andy Booth et al.
The Science of the total environment, 505, 596-605 (2014-12-03)
An aqueous dispersion of poly (acrylic acid)-stabilised cerium oxide (CeO₂) nanoparticles (PAA-CeO₂) was evaluated for its stability in a range of freshwater ecotoxicity media (MHRW, TG 201 and M7), with and without natural organic matter (NOM). In a 15 day...
Sami I Somo et al.
Tissue engineering. Part C, Methods, 21(8), 773-785 (2015-01-21)
Rapid and controlled vascularization within biomaterials is essential for many applications in regenerative medicine. The extent of vascularization is influenced by a number of factors, including scaffold architecture. While properties such as pore size and total porosity have been studied...
Yanli Zhao et al.
Drug development and industrial pharmacy, 40(11), 1483-1493 (2013-08-27)
The aim of the study is to synthesize a thiolated Pluronic copolymer, Pluronic-poly (acrylic acid)-cysteine copolymer, to construct a mixed micelle system with the Pluronic-poly (acrylic acid)-cysteine copolymer and Pluronic L121 (PL121) and to evaluate the potential of these mixed...
Amit K Jha et al.
PloS one, 9(6), e98640-e98640 (2014-06-18)
Osteogenic differentiation of human mesenchymal stem cells (hMSCs) is guided by various physical and biochemical factors. Among these factors, modulus (i.e., rigidiy) of the ECM has gained significant attention as a physical osteoinductive signal that can contribute to endochondral ossification...
É Petró et al.
Pharmaceutical development and technology, 20(3), 330-336 (2013-12-18)
The aim of the present work was to extend our previous in-vitro drug release studies using semisolid dermatological bases with non-impregnated cellulose acetate membranes. A comparison of the performances of two apparatuses, the more commonly used Franz cell and the...
Adrie J J Straathof et al.
Applied microbiology and biotechnology, 67(6), 727-734 (2005-03-01)
Acrylic acid might become an important target for fermentative production from sugars on bulk industrial scale, as an alternative to its current production from petrochemicals. Metabolic engineering approaches will be required to develop a host microorganism that may enable such...
S K Bajpai et al.
Journal of biomaterials science. Polymer edition, 26(14), 947-962 (2015-07-03)
Drug Gliclazide (Glz) has limited solubility and low bioavailability. In order to obtain a controlled release of this drug and to improve its bioavailability, the drug has been loaded into poly(caprolactone) (PCL)/poly(acrylic acid) (PAAc) hydrogels, prepared by free radical polymerization...
Luisa Islas et al.
International journal of pharmaceutics, 488(1-2), 20-28 (2015-04-22)
Acrylic acid (AAc) and poly(ethylene glycol) methacrylate (PEGMA) were singly and dually grafted onto poly(vinyl chloride) (PVC) urinary catheters with the aim of preventing biofouling by endowing the catheters with the ability to load and release antimicrobial agents and to...
Sandra Ritz et al.
Biomacromolecules, 16(4), 1311-1321 (2015-03-21)
Understanding nanoparticle-protein interactions is a crucial issue in the development of targeted nanomaterial delivery. Besides unraveling the composition of the nanoparticle's protein coronas, distinct proteins thereof could control nanoparticle uptake into specific cell types. Here we differentially analyzed the protein...
Jing Wu et al.
Journal of agricultural and food chemistry, 62(29), 7078-7084 (2014-07-08)
The high level of acrylamide in widely consumed processed foods poses a potentially significant risk to human health, which has led to an increasing demand for rapid, simple, and selective analytical methods. In the present work, several haptens for acrylamide...
Keisuke Kikuchi et al.
Chemical & pharmaceutical bulletin, 62(6), 559-567 (2014-06-03)
Two unique pressure-sensitive adhesive (PSA) tapes (PSA-A, -B) with different adhesive properties of commercial PSAs were prepared and evaluated for their usefulness as a pretreatment material prior to the application of transdermal therapeutic systems or topical drug formulations and also...
Yagahira E Castro-Sesquen et al.
PLoS neglected tropical diseases, 8(10), e3211-e3211 (2014-10-03)
Detection of congenital T. cruzi transmission is considered one of the pillars of control programs of Chagas disease. Congenital transmission accounts for 25% of new infections with an estimated 15,000 infected infants per year. Current programs to detect congenital Chagas...
Alex Hui et al.
Investigative ophthalmology & visual science, 55(8), 4896-4904 (2014-07-17)
The purpose of this study was to evaluate ciprofloxacin-releasing silicone hydrogel contact lens materials in vitro and in vivo for the treatment of microbial keratitis. Model silicone hydrogel contact lens materials were manufactured using a molecular imprinting technique to modify...
Raelle F Gomes et al.
Journal of colloid and interface science, 454, 200-209 (2015-06-04)
Robust and efficient methylene blue (MB) adsorbent was prepared based on starch/cellulose nanowhiskers hydrogel composite. Maximum MB adsorption capacity of ∼2050mgperg of dried hydrogel was obtained with the composite at 5wt.% of cellulose nanowhiskers and at pH 5. Adsorption capacity...
Zeynep Altintas et al.
Biosensors & bioelectronics, 74, 996-1004 (2015-08-13)
Comparative and comprehensive investigations for adenovirus recognition and detection were conducted using plastic and natural antibodies to compare three different strategies. The implementation of molecularly imprinted polymer (MIP) technology for specific and sensitive recognition of viruses with the combination of...
Yu Zheng et al.
Nature communications, 5, 5772-5772 (2014-12-17)
The self-assembly of nanoscale materials to form hierarchically ordered structures promises new opportunities in drug delivery, as well as magnetic materials and devices. Herein, we report a simple means to promote the self-assembly of two polymers with functional groups at...
Daniil Karnaushenko et al.
Advanced materials (Deerfield Beach, Fla.), 27(42), 6582-6589 (2015-09-24)
A novel method relying on strain engineering to realize arrays of on-chip-integrated giant magneto-impedance (GMI) sensors equipped with pick-up coils is put forth. The geometrical transformation of an initially planar layout into a tubular 3D architecture stabilizes favorable azimuthal magnetic...
Fang Sun et al.
ACS nano, 9(3), 2668-2676 (2015-03-05)
Reliable surface-enhanced Raman scattering (SERS) based biosensing in complex media is impeded by nonspecific protein adsorptions. Because of the near-field effect of SERS, it is challenging to modify SERS-active substrates using conventional nonfouling materials without introducing interference from their SERS...
Aleksandra Krstulja et al.
Journal of chromatography. A, 1365, 12-18 (2014-09-15)
A series of imprinted polymers targeting nucleoside metabolites, prepared using a template analogue approach, are presented. These were prepared following selection of the optimum functional monomer by solution association studies using (1)H NMR titrations whereby methacrylic acid was shown to...
Vincenzo Taresco et al.
Acta biomaterialia, 22, 131-140 (2015-04-29)
Microbial biofilms are known to support a number of human infections, including those related to medical devices. This work is focused on the development of novel dual-function amphiphilic random copolymers to be employed as coatings for medical devices. Particularly, copolymers...
You-Jin Kim et al.
Soft matter, 11(5), 994-1000 (2014-12-19)
A technique for adequate flow control is important in the fields of science and engineering. In this study, we hypothesized that the unrestricted flow control inside a chamber containing 'schools of magnetic particles' might be possible through control of an...
Shivaram Selvam et al.
Colloids and surfaces. B, Biointerfaces, 126, 35-43 (2014-12-30)
Injectable in situ crosslinking hydrogels offer unique advantages over conventional prefabricated hydrogel methodologies. Herein, we synthesize poly(xylitol-co-maleate-co-PEG) (pXMP) macromers and evaluate their performance as injectable cell carriers for tissue engineering applications. The designed pXMP elastomers were non-toxic and water-soluble with...
Chen Chen et al.
The journal of adhesive dentistry, 16(2), 169-176 (2014-04-01)
To evaluate the effects of a commercial zirconia primer (Choice or RelyX Unicem) on shear bond strength (SBS) of two different resin composite cements - Choice (a conventional bis-GMA-based resin cement) and RelyX Unicem (self-adhesive resin cement) - to zirconia....
H T P Nguyen et al.
Nanotechnology, 26(25), 255101-255101 (2015-06-03)
The cutaneous penetration of hydrophobic active molecules is of foremost concern in the dermatology and cosmetic formulation fields. The poor solubility in water of those molecules limits their use in hydrophilic forms such as gels, which are favored by patients...

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon


Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.