Showing 1-30 of 137 results for "V9879"
Peter Štefánik et al.
Pharmacology, biochemistry, and behavior, 131, 42-50 (2015-02-11)
Autism is a neurodevelopmental disorder characterised by the disruption of social interactions. Autistic animal models play a crucial role in neurophysiologic research on this disorder. One of these models is based on rats that have been prenatally treated with valproic...
Re: Vasopressin effectively suppresses male fertility.
Craig Niederberger
The Journal of urology, 190(4), 1343-1343 (2013-09-14)
Michael Lukas et al.
Psychoneuroendocrinology, 56, 35-44 (2015-03-25)
Although the involvement of the neuropeptide arginine vasopressin (AVP) in rodent social interaction is already extensively characterized, little is known about its role in social communication. Rats communicate in the ultrasonic range by means of ultrasonic vocalizations (USV). Depending on...
Toru Ishikura et al.
Journal of UOEH, 34(4), 315-321 (2012-12-29)
Physiological response to acute and chronic nociceptive stimulation are important for living organisms. In our laboratory, we generated transgenic rats expressing the arginine vasopressin (AVP) and enhanced green fluorescent protein (eGFP) fusion gene, and the c-fos and monomeric red fluorescent...
Joshua L Wang et al.
Annals of neurology, 78(2), 317-322 (2015-04-30)
The suprachiasmatic nucleus (SCN) of the hypothalamus, the master mammalian circadian pacemaker, synchronizes endogenous rhythms with the external day-night cycle. Older humans, particularly those with Alzheimer disease (AD), often have difficulty maintaining normal circadian rhythms compared to younger adults, but...
Kathleen M Meneely et al.
Archives of biochemistry and biophysics, 539(1), 70-80 (2013-09-24)
The isochorismate and salicylate synthases are members of the MST family of enzymes. The isochorismate synthases establish an equilibrium for the conversion chorismate to isochorismate and the reverse reaction. The salicylate synthases convert chorismate to salicylate with an isochorismate intermediate;...
Rare incorporation of bone marrow-derived cells into kidney after folic acid-induced injury
Szczypka MS, et al.
Stem Cells, 23(1), 44-54 (2005)
Amisha Wallia et al.
The Journal of clinical endocrinology and metabolism, 98(3), 881-886 (2013-02-09)
Postpartum, diabetes insipidus (DI) can be part of Sheehan's syndrome or lymphocytic hypophysitis in combination with anterior pituitary hormone deficiencies. In contrast, acute onset of isolated DI in the postpartum period is unusual. This patient presented at 33 weeks gestation...
Xiao-Feng Zhang et al.
Plant molecular biology, 83(3), 205-218 (2013-06-21)
Previous study showed that the magnesium-protoporphyrin IX chelatase H subunit (CHLH/ABAR) positively regulates abscisic acid (ABA) signaling. Here, we investigated the functions of a CHLH/ABAR interaction protein, the chloroplast co-chaperonin 20 (CPN20) in ABA signaling in Arabidopsis thaliana. We showed...
Feng Zheng et al.
European journal of anaesthesiology, 32(8), 563-570 (2015-08-06)
In contrast to other types of shock, anaphylactic shock decreases cerebral blood flow more than would be expected from severe arterial hypotension, thus potentially affecting survival through brain ischaemia/hypoxia. We hypothesised that epinephrine (EPI) used as a first-line treatment of...
Zhao-Huan Huang et al.
The Journal of comparative neurology, 528(6), 935-952 (2019-11-02)
The tree shrew (Tupaia belangeri chinensis) is the closest living relative of primates. Yet, little is known about the anatomical distribution of tyrosine hydroxylase (TH)-immunoreactive (ir) structures in the hypothalamus of the tree shrew. Here, we provide the first detailed...
Allison F Jaworski et al.
Archives of biochemistry and biophysics, 538(2), 138-144 (2013-08-24)
Cystathionine β-lyase (CBL) catalyzes the hydrolysis of l-cystathionine (l-Cth), producing l-homocysteine (l-Hcys), pyruvate and ammonia, in the second step of the transsulfuration pathway of bacteria and plants. A series of 17 site-directed variants of Escherichia coli CBL (eCBL) was constructed...
Sara Sabihi et al.
Psychoneuroendocrinology, 45, 31-42 (2014-05-23)
The neuropeptide oxytocin (OT) is anxiolytic in rodents and humans. However, the specific brain regions where OT acts to regulate anxiety requires further investigation. The medial prefrontal cortex (mPFC) has been shown to play a role in the modulation of...
Woo-Sung Kwon et al.
PloS one, 8(1), e54192-e54192 (2013-02-01)
Arginine vasopressin (VP) is neurohypophysial hormone has been implicated in stimulating contractile activity of the male reproductive tract in the testis. Higher levels of VP decrease sperm count and motility. However, very little is known about the involvement of VP...
Katrin N Sander et al.
Placenta, 88, 12-19 (2019-10-02)
The function of the placental vasculature differs considerably from other systemic vascular beds of the human body. A detailed understanding of the normal placental vascular physiology is the foundation to understand perturbed conditions potentially leading to placental dysfunction. Behaviour of...
E I Parker et al.
The British journal of radiology, 87(1033), 20130467-20130467 (2013-11-16)
Lysosomal storage diseases (LSDs) are a large group of genetic metabolic disorders that result in the accumulation of abnormal material, such as mucopolysaccharides, glycoproteins, amino acids and lipids, within cells. Since many LSDs manifest during infancy or early childhood, with...
Hari Prasad et al.
The Journal of physiology, 597(2), 499-519 (2018-09-23)
Significant and selective up-regulation of the Na+ /H+ exchanger NHA2 (SLC9B2) was observed in cysts of patients with autosomal dominant polycystic kidney disease. Using the MDCK cell model of cystogenesis, it was found that NHA2 increases cyst size. Silencing or...
Mingkwan Greenwood et al.
PloS one, 10(4), e0124956-e0124956 (2015-04-29)
Arginine vasopressin (AVP) is synthesised in magnocellular neurons (MCNs) of supraoptic nucleus (SON) and paraventricular nucleus (PVN) of the hypothalamus. In response to the hyperosmotic stressors of dehydration (complete fluid deprivation, DH) or salt loading (drinking 2% salt solution, SL)...
M Q Steinman et al.
Psychoneuroendocrinology, 51, 122-134 (2014-10-13)
Vasopressin signaling has important effects on the regulation of social behaviors and stress responses, and is considered a promising pathway to target for new therapeutics of stress-induced psychiatric disorders. Although there is evidence for sex differences in the behavioral effects...
Aki Kashiwazaki et al.
European journal of pharmacology, 765, 291-299 (2015-09-01)
Only limited information is available on agonist-dependent changes in the subcellular localization of vasopressin V1B receptors. Our radioligand binding study of membrane preparations and intact cells revealed that a large fraction of the V1B receptor is located in the cytoplasm...
Shantala Arundhati Hari Dass et al.
Molecular ecology, 23(24), 6114-6122 (2014-08-22)
Male rats (Rattus novergicus) infected with protozoan Toxoplasma gondii relinquish their innate aversion to the cat odours. This behavioural change is postulated to increase transmission of the parasite to its definitive felid hosts. Here, we show that the Toxoplasma gondii...
Daniel J van Wamelen et al.
Sleep, 36(1), 117-125 (2013-01-05)
To study whether sleep and circadian rhythm disturbances in patients with Huntington's disease (HD) arise from dysfunction of the body's master clock, the hypothalamic suprachiasmatic nucleus. Postmortem cohort study. Eight patients with HD and eight control subjects matched for sex...
Jose Marques-Lopes et al.
Synapse (New York, N.Y.), 69(3), 148-165 (2015-01-07)
Renin–angiotensin system overactivity, upregulation of postsynaptic NMDA receptor function, and increased reactive oxygen species (ROS) production in the hypothalamic paraventricular nucleus (PVN) are hallmarks of angiotensin II (AngII)-induced hypertension, which is far more common in young males than in young...
China N Byrns et al.
The Journal of biological chemistry, 289(14), 9662-9674 (2014-02-13)
Selenoproteins are a unique family of proteins, characterized by the co-translational incorporation of selenium as selenocysteine, which play key roles in antioxidant defense. Among selenoproteins, selenoprotein P (Sepp1) is particularly distinctive due to the fact that it contains multiple selenocysteine...
Silvia G Ruginsk et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 309(11), R1358-R1368 (2015-10-16)
The present study investigated the type 1 cannabinoid receptor (CB1R) as a potential candidate to mediate the homeostatic responses triggered by 24 h of water deprivation, which constitutes primarily a hydroelectrolytic challenge and also significantly impacts energy homeostasis. The present...
Jihwan Myung et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(29), E3920-E3929 (2015-07-02)
The mammalian suprachiasmatic nucleus (SCN) forms not only the master circadian clock but also a seasonal clock. This neural network of ∼10,000 circadian oscillators encodes season-dependent day-length changes through a largely unknown mechanism. We show that region-intrinsic changes in the...
Lone Brønd et al.
American journal of physiology. Renal physiology, 305(11), F1547-F1554 (2013-10-04)
A number of studies have shown that rats with congestive heart failure (CHF) have increased protein levels of the vasopressin (AVP)-regulated water channel aquaporin-2 (AQP2) even during conditions with unchanged circulating levels of AVP, suggesting an increase in the sensitivity...
Birgit Geueke et al.
Applied and environmental microbiology, 79(19), 6180-6183 (2013-07-23)
δ-Hexachlorocyclohexane (δ-HCH), one of the prevalent isomers of technical HCH, was enantioselectively dehydrochlorinated by the dehydrochlorinases LinA1 and LinA2 from Sphingobium indicum B90A to the very same δ-pentachlorocyclohexene enantiomer. Racemic δ-pentachlorocyclohexene, however, was transformed with opposite enantioselectivities by the two...
Michael P Greenwood et al.
Endocrinology, 156(8), 2905-2917 (2015-05-12)
The polyamines spermidine and spermine are small cations present in all living cells. In the brain, these cations are particularly abundant in the neurons of the paraventricular (PVN) and supraoptic nuclei (SON) of the hypothalamus, which synthesize the neuropeptide hormones...
Shujuan Sun et al.
Acta oto-laryngologica, 139(11), 966-976 (2019-09-20)
Background: To date, the pathogenesis of Meniere's disease (MD) remains unclear. Previous research found that the SLC4A1 gene significantly down-regulated. Aims: This study sought to understand the effect of SLC4A1 on the pathogenesis of MD. ELH C57 mice models were...

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