Showing 1-30 of 153 results for "

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E D Ehrenpreis et al.
Journal of clinical gastroenterology, 33(1), 36-40 (2001-06-22)
D-Xylose absorption testing is a simple, low-cost method of screening for small intestinal malabsorption. The optimum method to measure D-xylose absorption (serum vs. urine testing) is uncertain. We present a method of improving the accuracy of D-xylose testing. Fifty-one consecutive...
Junji Sashihara et al.
Virology, 391(2), 249-256 (2009-07-09)
Measurement of neutralizing antibodies to Epstein-Barr virus (EBV) is important for evaluation of candidate vaccines. The current neutralization assay is based on antibody inhibition of EBV transformation of B cells and requires 6 weeks to perform. We developed a rapid...
Larissa M Todero et al.
Bioprocess and biosystems engineering, 38(8), 1601-1613 (2015-05-04)
Isoamyl butyrate (banana flavor) was synthesized by esterification reaction of isoamyl alcohol and butyric acid in heptane medium. Immobilized Thermomyces lanuginosus lipase (TLL) prepared via physical adsorption on mesoporous poly-methacrylate particles (PMA) was used as biocatalyst. The factors that affect...
R Surtees et al.
Lancet (London, England), 335(8690), 619-621 (1990-03-17)
To assess methyl-group metabolism in the central nervous system in infection with human immunodeficiency virus (HIV), levels of 5-methyltetrahydrofolate, methionine, and S-adenosylmethionine were measured by high-performance liquid chromatography in cerebrospinal fluid (CSF) from six children with congenital HIV infection and...
Gili Berkovitch et al.
Journal of medicinal chemistry, 51(23), 7356-7369 (2008-11-15)
Multifunctional acyloxyalkyl ester prodrugs of 5-aminolevulinic acid in cancer cell lines inhibited the proteasome and induced apoptosis and heme synthesis. The most potent prodrug was butyryloxymethyl 5-amino-4-oxopentanoate (1a). The metabolically released formaldehyde from the prodrugs was the dominant factor affecting...
Vijay C Antharam et al.
Journal of clinical microbiology, 51(9), 2884-2892 (2013-06-28)
Clostridium difficile infection (CDI) causes nearly half a million cases of diarrhea and colitis in the United States each year. Although the importance of the gut microbiota in C. difficile pathogenesis is well recognized, components of the human gut flora...
Junya Zhang et al.
Bioresource technology, 200, 253-261 (2015-10-27)
The effects of microwave pretreatment (MW) on co-digestion of food waste (FW) and sewage sludge (SS) have never been investigated. In this study, a series of mesophilic biochemical methane potential (BMP) tests were conducted to determine the optimized ratio of...
Takashi Yamamura et al.
Anticancer research, 34(4), 1701-1708 (2014-04-03)
Tumor angiogenesis is a focus of molecularly-targeted therapies. This study investigated the effect of sodium butyrate (SB), a histone deacetylase inhibitor, on the synthesis of antiangiogenic and lymphangiogenic factors in oral squamous cell carcinoma. Gene alterations in HSC-3 cells were...
Silvia Cantoni et al.
The FEBS journal, 280(9), 2042-2055 (2013-03-08)
Sodium butyrate (BU) is a molecule that acts as a histone deacetylase inhibitor. As compared with its well-known antineoplastic/antiproliferative effects, little is known about BU action on vascular cell dynamics. An imbalance of proliferation and migration in pulmonary arterial smooth...
T Amani et al.
Water environment research : a research publication of the Water Environment Federation, 84(5), 460-472 (2012-08-03)
Volatile fatty acids (VFAs) are key intermediates in anaerobic digestion. Enriched acetogenic and methanogenic cultures were used for the syntrophic anaerobic digestion of VFAs in a continuous fixed-bed reactor at mesophilic conditions. The interactive effects of propionic (HPr), butyric (HBu)...
Giulia Caron et al.
Journal of medicinal chemistry, 48(9), 3269-3279 (2005-04-29)
Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in...
María Romo-Vaquero et al.
PloS one, 9(4), e94687-e94687 (2014-04-16)
Carnosic acid (CA) and rosemary extracts (RE) show body-weight, energy metabolism and inflammation regulatory properties in animal models but the mechanisms are not yet understood. Gut microbiota plays an important role in the host metabolism and inflammatory status and is...
S Khan et al.
Chemico-biological interactions, 213, 1-12 (2014-02-18)
Type 1 diabetes (T1D) also known as juvenile diabetes is a chronic autoimmune disorder that precipitates in genetically susceptible individuals by environmental factors particularly during early age. Both genetic and epigenetic factors are implicated in the beta-cell development, proliferation, differentiation...
G Bauer et al.
The Journal of biological chemistry, 257(19), 11411-11415 (1982-10-10)
Purified Epstein-Barr virus-inducing factor shows all the properties previously described for crude serum, i.e. inducing activity, cooperative activity with the inducers 12-O-tetradecanoyl-phorbol-13-acetate, 5'-iodo-2'-deoxyuridine, N-butyric acid, anti-IgM, and the need to be activated by pH shock. A small subpopulation of untreated...
Linda Hong et al.
Langmuir : the ACS journal of surfaces and colloids, 31(24), 6933-6941 (2015-06-02)
Liquid crystalline nanoparticles have shown great potential for application in fields of drug delivery and agriculture. However, optimized approaches to generating these dispersions have long been sought after. This study focused on understanding the mechanism of formation of cubosomes during...
Chunhui Zhang et al.
Current microbiology, 59(6), 656-663 (2009-09-04)
Several issues of butyric acid production with bacteria through fermentation are presented in this review. The current progress including the utilization of butyric acid, the production strains, the metabolic pathway, and regulation are presented in the paper. Process operation modes...
Keisuke Yaku et al.
Molecular and cellular biochemistry, 370(1-2), 7-14 (2012-07-19)
Dietary fiber fermentation by the colonic bacterial flora produces short-chain fatty acids, acetate, propionate and butyrate. Among them, butyrate is considered to be the major energy substrate for colonocytes and, at least in rats, seems to protect against colonic carcinogenesis....
Caroline Mongruel Eleutério Dos Santos et al.
Journal of food science, 80(6), C1170-C1177 (2015-04-30)
The amino acid profile in dessert apple must and its effect on the synthesis of fusel alcohols and esters in cider were established by instrumental analysis. The amino acid profile was performed in nine apple musts. Two apple musts with...
Meng Yu et al.
Molecular carcinogenesis, 53(7), 505-513 (2013-01-30)
Activation of telomerase is a key element in oncogenesis and resistance to apoptosis for many cancers. Some histone deacetylase inhibitors (HDACi) or chemotheraputic agents have been reported to downregulate the expression of human telomerase reverse transcriptase (hTERT). However, whether hTERT...
Yoshihiro Kadota et al.
Metabolism: clinical and experimental, 64(9), 1157-1164 (2015-06-25)
It has been reported that administration of octanoic acid, one of medium-chain fatty acids (MCFAs), promoted leucine oxidation in vitro and in vivo, but it remained unclear how octanoic acid stimulated leucine oxidation. Therefore, the aim of this study was...
Shuai Zhang et al.
International journal of molecular medicine, 30(6), 1431-1437 (2012-10-16)
Sodium butyrate (NaBu) is a short-chain fatty acid (SCFA), which has been proposed as a potential anticancer agent. Apoptosis-associated speck-like protein (ASC) is a pro-apoptotic signaling factor that is subjected to epigenetic silencing in human cancers. Modulation by the aberrant...
S Sánchez-Tena et al.
Biochimica et biophysica acta, 1832(12), 2264-2270 (2013-09-03)
Diet has a significant impact on colorectal cancer and both dietary fiber and plant-derived compounds have been independently shown to be inversely related to colon cancer risk. Butyrate (NaB), one of the principal products of dietary fiber fermentation, induces differentiation...
L McMillan et al.
British journal of cancer, 88(5), 748-753 (2003-03-06)
Butyrate, produced in the colon by fermentation of dietary fibre, induces apoptosis in colon adenoma and cancer cell lines, which may contribute to protection against colorectal cancer. However, butyrate is present in the colon along with other dietary factors, including...
Wenshu Liu et al.
The British journal of nutrition, 112(1), 15-29 (2014-04-30)
The aim of the present study was to investigate the effects of different dietary sustained-release microencapsulated sodium butyrate (MSB) products (0 (non-supplement), 1·5 and 3·0 h) for a control or oxidised soyabean oil (SBO) diet on fish production, intestinal mucosal...
Pingxi Xu et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(46), 16592-16597 (2014-10-29)
Insect repellents are important prophylactic tools for travelers and populations living in endemic areas of malaria, dengue, encephalitis, and other vector-borne diseases. DEET (N,N-diethyl-3-methylbenzamide) is a 6-decade-old synthetic repellent, which is still considered the gold standard of mosquito repellents. Mosquitoes...
Bashar Amer et al.
Lipids, 50(7), 681-689 (2015-05-27)
A comprehensive and accurate determination of free fatty acids (FFA) is required for fecal metabolomic investigations. The present study compares three aqueous extraction methods (1) ULTRA-TURRAX(®), (2) whirl mixing and (3) basic ULTRA-TURRAX extraction of fecal FFA with a direct...
G Bauer
International journal of cancer, 31(3), 291-295 (1983-03-15)
Corticosteroids can induce the synthesis of EBV antigens in the Burkitt lymphoma line Daudi. As early as 12 h after application of the drug, an increase of EA-positive cells can be seen, the maximum induction being reached after 2 days....
Tomoko Kurita-Ochiai et al.
Infection and immunity, 70(5), 2361-2367 (2002-04-16)
We previously demonstrated that butyric acid, an extracellular metabolite from periodontopathic bacteria, induces cytotoxicity and apoptosis in murine thymocytes, splenic T cells, and human Jurkat T cells. In this study, we used a cell-to-cell interaction system to examine the contribution...
Eduardo Baltierra-Trejo et al.
Bioresource technology, 196, 418-425 (2015-08-12)
The wheat straw lignin-rich fraction (WSLig-RF) can be used as a raw material for the production of metabolites for industrial use if ligninolytic mitosporic fungi are used for its biodegradation into aromatics and short-chain fatty acids (SCFAs, i.e., SCFA2-6). Although...
King-Yiu Lam et al.
The journal of physical chemistry. A, 116(50), 12229-12241 (2012-12-01)
The overall rate constants for the reactions of hydroxyl radicals (OH) with four small methyl esters, namely methyl formate (CH(3)OCHO), methyl acetate (CH(3)OC(O)CH(3)), methyl propanoate (CH(3)OC(O)C(2)H(5)), and methyl butanoate (CH(3)OC(O)C(3)H(7)), were investigated behind reflected shock waves using UV laser absorption...