Showing 1-30 of 247 results for "

W398500

"
Matthew Di Rago et al.
Forensic science international, 243, 35-43 (2014-05-06)
The aim of this study was to develop an LC-MS/MS based screening technique that covers a broad range of acidic and neutral drugs and poisons by combining a small sample volume and efficient extraction technique with simple automated data processing....
Kyle W Bender et al.
The Biochemical journal, 457(1), 127-136 (2013-10-10)
Many signalling pathways in plants are regulated by the second messenger calcium (Ca(2+)). In the standard model, Ca(2+)-sensor proteins, such as CaM (calmodulin), detect Ca(2+) signals and subsequently regulate downstream targets to advance the signal transduction cascade. In addition to...
Jinyoung Kwak et al.
Langmuir : the ACS journal of surfaces and colloids, 29(14), 4477-4484 (2013-03-20)
Photoluminescent spherical nanostructures were prepared through the self-assembly of a tyrosine-containing bolaamphiphilic molecule, and their antenna effect was examined. The photoluminescent spherical nanostructures were simply prepared by self-assembly of bolaamphiphile molecules in an aqueous solution in which water-soluble photosensitizers and...
E Hazouard et al.
Journal francais d'ophtalmologie, 22(1), 73-75 (1999-04-30)
We report a case of salicylism caused by association of acetylsalicylic acid (ASA) and acetazolamide. A 50-year-old woman without chronic renal insufficiency, was admitted for confusion, cerebellar ataxia associated with hyperchloremic acidosis. She was treated with acetazolamide for simple glaucoma...
Sima Panahirad et al.
Journal of the science of food and agriculture, 94(9), 1758-1763 (2013-11-26)
One of the most important saprophytic infections in fresh pistachio fruits after harvesting is Aspergillus flavus colonization, which significantly reduces fruit quality. Salicylic acid plays a crucial role in plant tissues and has a suppression effect on some fungi. The...
P Patrignani et al.
Journal of thrombosis and haemostasis : JTH, 12(8), 1320-1330 (2014-06-20)
Even though the acetylation of platelet cyclooxygenase (COX)-1 at serine-529 is the direct mechanism of action of low-dose aspirin, its antiplatelet effect has been characterized using indirect indexes of COX-1 activity. We performed a clinical study with enteric-coated low-dose aspirin...
Jae-Young Je et al.
Food & function, 6(6), 1911-1918 (2015-05-13)
Naturally occurring phenolic compounds are widely found in plants. Here, the phenolic composition and hepatoprotective effect of the butanolic extract (BE) from Nelumbo nucifera leaves against H2O2-induced hepatic damage in cultured hepatocytes were investigated. BE showed high total phenol and...
Seung Ho Chung et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(39), 15728-15733 (2013-09-11)
Induced plant defenses in response to herbivore attack are modulated by cross-talk between jasmonic acid (JA)- and salicylic acid (SA)-signaling pathways. Oral secretions from some insect herbivores contain effectors that overcome these antiherbivore defenses. Herbivores possess diverse microbes in their...
Mireia Núñez et al.
Analytical and bioanalytical chemistry, 407(13), 3841-3849 (2015-03-18)
A method for the quantitative determination of seven pharmaceuticals in bivalves was developed by QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) extraction, followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) with electrospray ionization. Both the European Standard Method EN 15662...
Jo Ann E Asselin et al.
Plant physiology, 167(3), 1117-1135 (2015-01-31)
AvrE family type III effector proteins share the ability to suppress host defenses, induce disease-associated cell death, and promote bacterial growth. However, despite widespread contributions to numerous bacterial diseases in agriculturally important plants, the mode of action of these effectors...
Salicylic acid: properties, biosynthesis and physiological role.
Popova L, et al.
Bulgarian Journal of Plant Physiology, 23(1-2), 85-93 (1997)
Kimiko Fukuoka et al.
Biodegradation, 26(5), 359-373 (2015-07-02)
3-Methylindole, also referred to as skatole, is a pollutant of environmental concern due to its persistence, mobility and potential health impacts. Petroleum refining, intensive livestock production and application of biosolids to agricultural lands result in releases of 3-methylindole to the...
Giorgio Ottaviani et al.
Journal of medicinal chemistry, 49(13), 3948-3954 (2006-06-23)
This work was devoted to the search for new artificial membranes allowing a rapid evaluation of passive human skin permeation of compounds with a parallel artificial membrane permeability assay (PAMPA). Effective permeability coefficients (Pe) determined for a set of compounds...
Rona Reibis et al.
Current medical research and opinion, 31(2), 211-219 (2014-10-18)
We aimed to describe the contemporary management of patients with systolic chronic heart failure (CHF) during a cardiac rehabilitation (CR) stay and present outcomes with focus on lipids, blood pressure, exercise capacity, and clinical events. Comparison of 3199 patients with...
V A Halim et al.
Plant biology (Stuttgart, Germany), 8(3), 307-313 (2006-06-30)
Phytohormones are not only instrumental in regulating developmental processes in plants but also play important roles for the plant's responses to biotic and abiotic stresses. In particular, abscisic acid, ethylene, jasmonic acid, and salicylic acid have been shown to possess...
Renu Rajguru
Aviation, space, and environmental medicine, 84(12), 1268-1276 (2014-01-28)
Modern-day high performance aircraft are more powerful, more efficient, and, unfortunately, frequently produce high noise levels, resulting in noise-induced hearing loss (NIHL) in military aircrew. Military pilots are required to perform many flight duties correctly in the midst of many...
David Buttar et al.
Bioorganic & medicinal chemistry, 18(21), 7486-7496 (2010-09-28)
The displacement of probes that bind selectively to subdomains IIA or IIIA on human serum albumin (HSA) by competing compounds has been followed using fluorescence spectroscopy, and has therefore been used to assign a primary binding site for these compounds...
Gregory Kaler et al.
The Journal of biological chemistry, 282(33), 23841-23853 (2007-06-08)
Organic anion transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine their substrate selectivity. We examined the substrate binding preferences and transport function of...
A Quaranta et al.
Audiology : official organ of the International Society of Audiology, 38(3), 174-179 (1999-08-07)
The aim of this study was to evaluate, in young volunteer subjects, the effects of salicylates on evoked otoacoustic emissions (EOAEs), which presumably reflect an active mechanical process in the cochlea due to outer hair cell (OHC) activity, and on...
Esra Bayram et al.
Bioorganic & medicinal chemistry, 16(20), 9101-9105 (2008-09-30)
The inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2.1.1) isozymes, hCA I and II, with a series of salicylic acid derivatives was investigated by using the esterase method with 4-nitrophenyl acetate as substrate. IC(50) values for sulfasalazine, diflunisal...
Francesco Epifano et al.
Bioorganic & medicinal chemistry letters, 17(20), 5709-5714 (2007-09-05)
Different esters of 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid (1), an anti-inflammatory principle of Acronychia baueri Schott (Rutaceae), were synthesized. Their topical anti-inflammatory activity was evaluated using the Croton oil ear test in mice as a model of acute inflammation. The activity of...
Tatjana Peskan-Berghöfer et al.
The New phytologist, 208(3), 873-886 (2015-06-16)
Root colonization by the beneficial fungus Piriformospora indica is controlled by plant innate immunity, but factors that channel this interaction into a mutualistic relationship are not known. We have explored the impact of abscisic acid (ABA) and osmotic stress on...
Shuichi Fukuoka et al.
Scientific reports, 5, 7773-7773 (2015-01-15)
Effective control of blast, a devastating fungal disease of rice, would increase and stabilize worldwide food production. Resistance mediated by quantitative trait loci (QTLs), which usually have smaller individual effects than R-genes but confer broad-spectrum or non-race-specific resistance, is a...
Evangelia Terzopoulou et al.
Environmental science and pollution research international, 22(2), 1095-1112 (2014-08-12)
A multi-residue method, based on gas chromatography coupled to tandem mass spectrometry (GC-MS/MS), has been developed for the determination of 70 organic micropollutants from various chemical classes (organochlorinated, organophosphorous, triazines, carbamate and urea, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, pharmaceuticals, phenols...
Katrin Scheit et al.
Carcinogenesis, 36(3), 400-411 (2015-02-06)
Salicylic acid and anthocyanidins are known as plant-derived antioxidants, but also can provoke paradoxically seeming prooxidant effects in vitro. These prooxidant effects are connected to the potential of salicylic acid and anthocyanidins to induce apoptosis selectively in tumor cells in...
Jason T Bau et al.
Molecular pharmacology, 85(2), 198-207 (2013-11-14)
Topoisomerase II (topo II) is a ubiquitous enzyme that is essential for cell survival through its role in regulating DNA topology and chromatid separation. Topo II can be poisoned by common chemotherapeutics (such as doxorubicin and etoposide), leading to the...
J Musembi Mutuku et al.
Plant physiology, 168(3), 1152-1163 (2015-05-31)
The root hemiparasite witchweed (Striga spp.) is a devastating agricultural pest that causes losses of up to $1 billion US annually in sub-Saharan Africa. Development of resistant crops is one of the cost-effective ways to address this problem. However, the...
Zheng Qing Fu et al.
Annual review of plant biology, 64, 839-863 (2013-02-05)
Systemic acquired resistance (SAR) is an induced immune mechanism in plants. Unlike vertebrate adaptive immunity, SAR is broad spectrum, with no specificity to the initial infection. An avirulent pathogen causing local programmed cell death can induce SAR through generation of...
Chuanfu An et al.
Journal of integrative plant biology, 53(6), 412-428 (2011-05-04)
The small phenolic compound salicylic acid (SA) plays an important regulatory role in multiple physiological processes including plant immune response. Significant progress has been made during the past two decades in understanding the SA-mediated defense signaling network. Characterization of a...
N I Vasiukova et al.
Prikladnaia biokhimiia i mikrobiologiia, 43(4), 405-411 (2007-10-13)
Current understanding of the involvement of salicylic acid (SA) in the formation of plant resistance has been reviewed. SA acts as a signal molecule in the SA-dependent pathway. The so-called salicylate burst observed in tissues of plants after stress increases...