Showing 1-30 of 1073 results for "W4502"
E D Son et al.
Clinical and experimental dermatology, 40(3), 247-253 (2014-12-17)
Maintenance of water balance in the stratum corneum (SC) is determined by the content of intercellular lipids and natural moisturizing factors (NMFs) in corneocytes. To investigate the association between the NMFs and (pro)filaggrin and the proteases responsible for the processing...
Guomin Ai et al.
Journal of chromatography. A, 1356, 283-288 (2014-07-06)
During gas chromatography/mass spectrometry (GC-MS) analyses using water and methanol as injection solvents, hydrolysis reactions after injecting water control and alcoholysis reactions after injecting methanol control or ethanol into a GC-MS system were observed and studied. Two dominant hydrolysis/alcoholysis product...
A G Ivanov et al.
Journal of photochemistry and photobiology. B, Biology, 152(Pt B), 335-346 (2015-09-01)
Comparative analysis of in vivo chlorophyll fluorescence imaging revealed that photosystem II (PSII) photochemical efficiency (Fv/Fm) of leaves of the Costata 2/133 pea mutant with altered pigment composition and decreased level of oligomerization of the light harvesting chlorophyll a/b-protein complexes...
Rafael C Lajmanovich et al.
Environmental research, 136, 205-212 (2014-12-03)
The effects of commercial formulations of Bacillus thuringiensisvar.israelensis (Bti) on non-target organisms are still a matter of debate; in amphibians, the risks of Bti are little known. To evaluate the toxicity of a commercial liquid (aqueous suspension, AS) formulation of...
K Giewekemeyer et al.
Biophysical journal, 109(9), 1986-1995 (2015-11-05)
The structural investigation of noncrystalline, soft biological matter using x-rays is of rapidly increasing interest. Large-scale x-ray sources, such as synchrotrons and x-ray free electron lasers, are becoming ever brighter and make the study of such weakly scattering materials more...
Fang Yuan et al.
Nature, 514(7522), 367-371 (2014-08-28)
Water is crucial to plant growth and development. Environmental water deficiency triggers an osmotic stress signalling cascade, which induces short-term cellular responses to reduce water loss and long-term responses to remodel the transcriptional network and physiological and developmental processes. Several...
Takashi Fujii et al.
Nature protocols, 10(9), 1445-1456 (2015-08-28)
Live single-cell mass spectrometry (live MS) provides a mass spectrum that shows thousands of metabolite peaks from a single live plant cell within minutes. By using an optical microscope, a cell is chosen for analysis and a metal-coated nanospray microcapillary...
Irina Gradinaru et al.
PloS one, 10(11), e0142787-e0142787 (2015-11-17)
α1a Adrenergic receptors (α1aARs) are the predominant AR subtype in human vascular smooth muscle cells (SMCs). α1aARs in resistance vessels are crucial in the control of blood pressure, yet the impact of naturally occurring human α1aAR genetic variants in cardiovascular...
Maegan L Capitano et al.
Blood cells, molecules & diseases, 55(1), 15-20 (2015-05-16)
Ames hypopituitary dwarf mice are deficient in growth hormone, thyroid-stimulating hormone, and prolactin. The phenotype of these mice demonstrates irregularities in the immune system with skewing of the normal cytokine milieu towards a more anti-inflammatory environment. However, the hematopoietic stem...
Seung-Ho Shin et al.
PloS one, 10(9), e0137011-e0137011 (2015-09-04)
Congenital cholesteatomas are epithelial lesions that present as an epithelial pearl behind an intact eardrum. Congenital and acquired cholesteatomas progress quite differently from each other and progress patterns can provide clues about the unique origin and pathogenesis of the abnormality....
Jinggeng Zhou et al.
Journal of experimental botany, 66(11), 3353-3366 (2015-04-16)
Regulating the intensity and duration of immune responses is crucial to combat infections without deleterious side effects. Arabidopsis FLS2, the receptor for bacterial flagellin, activates immune signalling by association with its partner BAK1. Upon flagellin (flg22) perception, the plant U-box...
Anand Dusad et al.
Immunologic research, 62(1), 46-59 (2015-03-12)
Systemic bone loss is associated with airway inflammatory diseases; yet, strategies to halt disease progression from inhalant exposures are not clear. Vitamin D might be a potentially protective approach against noxious respirable environmental exposures. We sought to determine whether vitamin...
Karen S Sarkisyan et al.
Biophysical journal, 109(2), 380-389 (2015-07-23)
Spectral diversity of fluorescent proteins, crucial for multiparameter imaging, is based mainly on chemical diversity of their chromophores. Recently we have reported, to our knowledge, a new green fluorescent protein WasCFP-the first fluorescent protein with a tryptophan-based chromophore in the anionic...
Kathrin Zimmermann et al.
Journal of immunology (Baltimore, Md. : 1950), 194(2), 637-649 (2014-12-05)
Progressive quantitative and qualitative decline of CD4(+) T cell responses is one hallmark of HIV-1 infection and likely depends on several factors, including a possible contribution by the HIV-1 envelope glycoprotein gp120, which binds with high affinity to the CD4...
Marija Matulionytė et al.
Journal of biomedical optics, 20(5), 051018-051018 (2014-12-18)
Ultrasmall photoluminescent gold nanoclusters (Au NCs), composed of several atoms with sizes up to a few nanometers, have recently stimulated extensive interest. Unique molecule-like behaviors, low toxicity, and facile synthesis make photoluminescent Au NCs a very promising alternative to organic...
Tingquan Wu et al.
Gene, 549(2), 214-222 (2014-07-30)
L-type lectin receptor kinase (LecRK) proteins are an important family involved in diverse biological processes such as pollen development, senescence, wounding, salinity and especially in innate immunity in model plants such as Arabidopsis and tobacco. Till date, LecRK proteins or...
Victor A Brugman et al.
Parasites & vectors, 8, 421-421 (2015-08-15)
Determining the host feeding patterns of mosquitoes by identifying the origin of their blood-meals is an important part of understanding the role of vector species in current and future disease transmission cycles. Collecting large numbers of blood-fed mosquitoes from the...
Maria Mellinas-Gomez et al.
BMC veterinary research, 11, 215-215 (2015-08-19)
Cancer is the leading cause of death in older dogs and its prevalence is increasing. There is clearly a need to develop more effective anti-cancer drugs in dogs. SG2000 (SJG-136) is a sequence selective DNA minor groove cross-linking agent. Based...
Jesse K Kreye et al.
Ecological applications : a publication of the Ecological Society of America, 23(8), 1976-1986 (2014-02-22)
Long-term fire exclusion has altered ecological function in many forested ecosystems in North America. The invasion of fire-sensitive tree species into formerly pyrogenic upland forests in the southeastern United States has resulted in dramatic shifts in surface fuels that have...
Malgorzata Frik et al.
Journal of medicinal chemistry, 57(23), 9995-10012 (2014-11-20)
A series of organometallic ruthenium(II) complexes containing iminophosphorane ligands have been synthesized and characterized. Cationic compounds with chloride as counterion are soluble in water (70-100 mg/mL). Most compounds (especially highly water-soluble 2) are more cytotoxic to a number of human...
Szu-Ting Lin et al.
Cellular and molecular life sciences : CMLS, 72(12), 2395-2409 (2015-01-19)
Chemotherapy is one of the major categories of medical oncology and a primary tumor treatment; however, the effectiveness of chemotherapy is restricted by drug resistance. Overcoming resistance to chemotherapy and investigating molecular targeted therapies are challenges currently faced during resistance...
Martina Pičmanová et al.
The Biochemical journal, 469(3), 375-389 (2015-07-25)
Cyanogenic glycosides are phytoanticipins involved in plant defence against herbivores by virtue of their ability to release toxic hydrogen cyanide (HCN) upon tissue disruption. In addition, endogenous turnover of cyanogenic glycosides without the liberation of HCN may offer plants an...
Victor S Van Laar et al.
Neurobiology of disease, 74, 180-193 (2014-12-06)
Disruption of the dynamic properties of mitochondria (fission, fusion, transport, degradation, and biogenesis) has been implicated in the pathogenesis of neurodegenerative disorders, including Parkinson's disease (PD). Parkin, the product of gene PARK2 whose mutation causes familial PD, has been linked...
Tuan-Ti Hsu et al.
Journal of endodontics, 41(7), 1073-1080 (2015-04-13)
Mineral trioxide aggregate (MTA) has been successfully used in clinical applications in endodontics. Studies show that the antibacterial effects of CO2 laser irradiation are highly efficient when bacteria are embedded in biofilm because of a photothermal mechanism. The aim of...
M Bernier et al.
Journal of economic entomology, 107(2), 531-537 (2014-04-30)
The pupal development of Aethina tumida Murray (Coleoptera: Nitidulidae) was studied at various combinations of thermo-hygrometric soil conditions (temperatures of 16, 18, and 20 degrees C and soil water content levels of 0.37, 0.56, and 0.73 m3 water per cubic...
Eva C Bach et al.
PloS one, 10(3), e0121022-e0121022 (2015-03-24)
A variety of metabolic disorders, including complications experienced by diabetic patients, have been linked to altered neural activity in the dorsal vagal complex. This study tested the hypothesis that augmentation of N-Methyl-D-Aspartate (NMDA) receptor-mediated responses in the vagal complex contributes...
Daniel Alexandre Menezes Pedrosa Malta et al.
The journal of adhesive dentistry, 16(6), 517-522 (2014-12-18)
To assess the resin microtensile bond strength (MTBS) and the monomer conversion (MC) of indirect composite resin restorations made of three different materials. Two light-polymerized direct materials (Filtek Z100 and Premise) and one light- and heat-polymerized indirect material (Premise Indirect)...
J P Dubey et al.
Parasitology, 142(13), 1555-1562 (2015-08-26)
The North American opossum (Didelphis virginiana) is the definitive host for at least three named species of Sarcocystis: Sarcocystis falcatula, Sarcocystis neurona and Sarcocystis speeri. The South American opossums (Didelphis albiventris, Didelphis marsupialis and Didelphis aurita) are definitive hosts for...
Michihiro Suga et al.
Nature, 517(7532), 99-103 (2014-12-04)
Photosynthesis converts light energy into biologically useful chemical energy vital to life on Earth. The initial reaction of photosynthesis takes place in photosystem II (PSII), a 700-kilodalton homodimeric membrane protein complex that catalyses photo-oxidation of water into dioxygen through an...
Jane Kilcoyne et al.
Journal of agricultural and food chemistry, 63(20), 5083-5091 (2015-04-25)
Azaspiracids (AZAs) are marine biotoxins produced by dinoflagellates that can accumulate in shellfish, which if consumed can lead to poisoning events. AZA7-10, 7-10, were isolated from shellfish and their structures, previously proposed on the basis of only LC-MS/MS data, were...

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