Showing 1-30 of 13063 results for "X100"
Samantha T Clark et al.
Colloids and surfaces. B, Biointerfaces, 187, 110609-110609 (2019-12-07)
The effects of lipid charge and head group size on liposome partitioning by detergents is an important consideration for applications such as liposomal drug delivery or proteoliposome formation. Yet, the solubilization of mixed-lipid liposomes, those containing multiple types of lipids...
Mohsen Saeedi et al.
Journal of environmental management, 214, 204-214 (2018-03-12)
The effects of soil components such as clay minerals and as humic acids, as well as co-existing metals and polycyclic aromatic hydrocarbons, on desorption and mobility are examined. Three types of artificially blended clay and clay mineral mixtures (pure kaolinite...
Marta Vignola et al.
Water research, 143, 66-76 (2018-06-26)
Rapid quantification of absolute microbial cell abundances is important for a comprehensive interpretation of microbiome surveys and crucial to support theoretical modelling and the design of engineered systems. In this paper, we propose a protocol specifically optimised for the quantification...
Roberto Gaetani et al.
Tissue engineering. Part C, Methods (2018-11-07)
Different approaches have investigated the effects of the different extracellular matrices (ECMs) and 3D culture on islets function, showing encouraging results. Ideally, the proper scaffold should mimic the biochemical composition of the native tissue as it drives numerous signaling pathways...
Zhaoguo Han et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 59(11), 1686-1691 (2018-05-20)
Elevated expression of the c-Met receptor plays a crucial role in cancers. In non-small cell lung cancer (NSCLC), aberrant activation of the c-Met signaling pathway contributes to tumorigenesis and cancer progression and may mediate acquired resistance to epidermal growth factor...
Hossein Aleyasin et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(26), 5913-5924 (2018-06-13)
A growing number of studies implicate the brain's reward circuitry in aggressive behavior. However, the cellular and molecular mechanisms within brain reward regions that modulate the intensity of aggression as well as motivation for it have been underexplored. Here, we...
Abubakar Wani et al.
Autophagy, 15(10), 1810-1828 (2019-03-22)
Imbalance in production and clearance of amyloid beta (Aβ) is the primary reason for its deposition in Alzheimer disease. Macroautophagy/autophagy is one of the important mechanisms for clearance of both intracellular and extracellular Aβ. Here, through screening, we identified alborixin...
Courtney J McCann et al.
Metallomics : integrated biometal science, 11(6), 1128-1139 (2019-05-10)
Single nucleotide polymorphisms (SNPs) are the largest source of sequence variation in the human genome. However, their functional significance is not well understood. We show that SNPs in the Wilson disease gene, ATP7B, that produce amino-acid substitutions K832R and R952K...
Jung-Min Kim et al.
Nature communications, 11(1), 2289-2289 (2020-05-10)
The osteoblast differentiation capacity of skeletal stem cells (SSCs) must be tightly regulated, as inadequate bone formation results in low bone mass and skeletal fragility, and over-exuberant osteogenesis results in heterotopic ossification (HO) of soft tissues. RUNX2 is essential for...
Alvaro Molina-Cruz et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(5), 2597-2605 (2020-01-24)
The surface protein Pfs47 allows Plasmodium falciparum parasites to survive and be transmitted by making them "undetectable" to the mosquito immune system. P. falciparum parasites express Pfs47 haplotypes compatible with their sympatric vectors, while those with incompatible haplotypes are eliminated...
Alexandra A DeSmidt et al.
Anatomical record (Hoboken, N.J. : 2007), 303(3), 544-555 (2019-03-16)
Hereditary deafness is often a neurosensory disorder and affects the quality of life of humans. Only three X-linked genes (POU class 3 homeobox 4 (POU3F4), phosphoribosyl pyrophosphate synthetase 1 (PRPS1), and small muscle protein X-linked (SMPX)) are known to be...
Haichong Wu et al.
Oncotarget, 8(12), 20042-20055 (2017-02-23)
The purpose of this study was to investigate the effects of thymol on lipopolysaccharide (LPS)-induced inflammatory responses and to clarify the potential mechanism of these effects. LPS-induced mouse endometritis was used to confirm the anti-inflammatory action of thymol in vivo....
Juliane C Campos et al.
Autophagy, 13(8), 1304-1317 (2017-06-10)
We previously reported that facilitating the clearance of damaged mitochondria through macroautophagy/autophagy protects against acute myocardial infarction. Here we characterize the impact of exercise, a safe strategy against cardiovascular disease, on cardiac autophagy and its contribution to mitochondrial quality control...
Hasna Ahyayauch et al.
Chemistry and physics of lipids, 167-168, 57-61 (2013-03-05)
The early stages of Triton X-100 solubilization of bilayers consisting of sphingomyelin/ceramide (SM/Cer) mixtures have been studied using a combination of calorimetric and spectroscopic techniques. Compositions based on sphingomyelin, containing up to 30 mol% Cer, at 4, 20 and 50°C...
Wei Liu et al.
Journal of materials science. Materials in medicine, 26(7), 203-203 (2015-07-15)
The β-titanium alloy is thought to be a promising alloy using as orthopedic or dental implants owing to its characteristics, which contains low elastic modulus, high corrosion resistance and well biocompatibility. Our previous study has reported that a new β-titanium...
Dimitris J Panagopoulos
International journal of radiation biology, 92(2), 94-106 (2015-12-15)
Purpose To study the effect of pulsed electric field - applied in corona discharge photography - on Drosophila melanogaster reproduction, possible induction of DNA fragmentation, and morphological alterations in the gonads. Materials and methods Animals were exposed to different field...
Sandra Milena Bernal Ulloa et al.
Zygote (Cambridge, England), 23(3), 367-377 (2014-01-16)
Cyclic adenosine monophosphate (cAMP) modulators have been used to avoid spontaneous oocyte maturation and concomitantly improve oocyte developmental competence. The current work evaluated the effects of the addition of cAMP modulators forskolin, 3-isobutyl-1-methylxanthine (IBMX) and cilostamide during in vitro maturation...
R Gonzalez-Castro et al.
Inflammopharmacology, 26(3), 817-827 (2017-11-03)
The main amyloid-beta (Aβ) variants detected in the human brain are full-length Aβ1-40 and Aβ1-42 peptides; however, a significant proportion of AD brain Aβ consists also of N-terminal truncated/modified species. The majority of the previous immunotherapeutic strategies targeted the N-terminal...
Uthra Rajamani et al.
Cell stem cell, 22(5), 698-712 (2018-04-24)
The hypothalamus contains neurons that integrate hunger and satiety endocrine signals from the periphery and are implicated in the pathophysiology of obesity. The limited availability of human hypothalamic neurons hampers our understanding of obesity disease mechanisms. To address this, we...
April Andrews et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(5), 1588-1600 (2018-12-01)
Unique cells characterized by multipotency, self-renewal, and high tumorigenic potential have been recently discovered in mucoepidermoid carcinomas. These cells are defined by high aldehyde dehydrogenase activity and high CD44 expression (ALDHhighCD44high) and function as cancer stem cells (CSC). It has...
Mean Ghim et al.
Journal of biological engineering, 12, 15-15 (2018-08-22)
Effects of shear stress on endothelium are important for the normal physiology of blood vessels and are implicated in the pathogenesis of atherosclerosis. They have been extensively studied in vitro. In one paradigm, endothelial cells are cultured in devices that...
Cataldo Pignatelli et al.
Acta biomaterialia, 73, 365-376 (2018-04-21)
Human platelet lysate (hPL) is a pool of growth factors and cytokines able to induce regeneration of different tissues. Despite its good potentiality as therapeutic tool for regenerative medicine applications, hPL has been only moderately exploited in this field. A...
Fatma M Abdel-Maksoud et al.
Scientific reports, 9(1), 4507-4507 (2019-03-16)
Telocytes (TCs) are a distinct stromal cell type described in many organs. The present study investigated the existence of TCs within the efferent ductules in camel and the changes that occur in their morphology and activity during active and inactive...
Mario Bianco et al.
PloS one, 14(6), e0218986-e0218986 (2019-06-30)
In unilateral ureteral obstruction (UUO), both oxidative stress and mitochondrial dysfunction are related to cell death. The aim of this study has been to characterize profiles of enzyme antioxidant activities and mitochondrial functioning of the contralateral (CL) compared to UUO...
Teresa H Wen et al.
Cerebral cortex (New York, N.Y. : 1991), 28(11), 3951-3964 (2017-10-19)
Abnormal sensory responses associated with Fragile X Syndrome (FXS) and autism spectrum disorders include hypersensitivity and impaired habituation to repeated stimuli. Similar sensory deficits are also observed in adult Fmr1 knock-out (KO) mice and are reversed by genetic deletion of...
Sadie E Nennig et al.
Alcoholism, clinical and experimental research, 44(3), 600-610 (2020-01-21)
Comorbidity between alcoholism and depression is extremely common. Recent evidence supports a relationship between alcohol exposure and stress sensitivity, an underlying factor in the development of depression. Our laboratory has recently shown that chronic alcohol gavage increases sensitivity to social...
Sang-Jin Yu et al.
Cell transplantation, 26(2), 365-377 (2016-09-30)
Human mesenchymal stem cells (hMSCs) are self-renewing cells with the ability to differentiate into organized, functional network of cells. Recent studies have revealed that activation of the Wnt/β-catenin pathway by a glycogen synthase kinase (GSK)-3-specific pharmacological inhibitor, Bio, results in...

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