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Leonard Mutsokoti et al.
Food chemistry, 232, 124-134 (2017-05-12)
The micellar incorporation of carotenoids (lycopene, α- and β-carotene) and lipid digestion products (free fatty acids, FFAs, and monoacylglycerides, MAGs) during in vitro digestion of oil-in-water emulsions was investigated by a kinetic approach. A fractional conversion model could adequately describe
Min-Yee Choo et al.
Materials (Basel, Switzerland), 13(14) (2020-07-16)
Nickel-based catalysts play an important role in the hydrogen-free deoxygenation for the production of biofuel. The yield and quality of the biofuel are critically affected by the physicochemical properties of NiO supported on nanosized zeolite Y (Y65, crystal size of
Kazunori Iwanaga et al.
Archives of pharmacal research, 37(7), 937-946 (2013-10-02)
The purpose of this study was to quantitatively clarify the effect of alky-chain length of a triglyceride in an emulsion on the partitioning of highly lipophilic compounds into the lymph fluid after their oral administration. Highly lipophilic anthraquinone derivatives were
Xuchun Qiu et al.
Chemosphere, 220, 687-695 (2019-01-04)
The ubiquitous environmental obesogens tributyltin (TBT) and perfluorooctane sulfonate (PFOS) may accumulate in parent and be transferred to their offspring, resulting in trans-generational adverse effects. In this study, we investigated the combined toxic and obesogenic effects of TBT and PFOS
Ronit Mesilati-Stahy et al.
PloS one, 13(12), e0209565-e0209565 (2019-01-01)
The effects of the macrostructure of long chain fatty acids on the lipid metabolism and biosynthesis of lipid droplets (LD) was studied in mammary epithelial cells (MEC). MEC were exposed to similar compositions and concentrations of fatty acids in the
Lijun Liu et al.
Bioresource technology, 262, 342-346 (2018-05-08)
Acetate and ammonium were used as organic carbon and nitrogen sources, respectively, during mixotrophic cultivation of Chlorella pyrenoidosa. Cell growth, content of neutral lipid (NL), productivity of biomass and total lipid, and fatty acid profiles were investigated. Results showed that
Thomas Alan Kwan et al.
Bioresource technology, 269, 81-88 (2018-08-28)
Clustering behavior of supercritical carbon dioxide, triacylglycerides, and astaxanthin solutes were analyzed using Kamlet-Taft solvatochromic properties of dipolarity/polarizability, π∗, and hydrogen-bond acceptance, β. Both parameters were decreased for supercritical carbon dioxide with TAG at low densities and with astaxanthin at
Hédia Manai-Djebali et al.
Journal of oleo science, 67(4), 379-388 (2018-03-13)
The chemical composition of extra virgin olive oils (EVOOs) from six new progenies, obtained through controlled crossings between the main Tunisian variety Chemlali and autochthonous (Chemcheli) and foreign cultivars (Sigoise, Coratina, Koroneiki, and Arbequina) used as pollen acceptor or pollinator
Harry Martin et al.
Food & function, 8(9), 3339-3345 (2017-08-30)
Kiwifruit contains the cysteine proteinase actinidin whose strong activity allows kiwifruit to be used as a meat tenderiser. This raises the possibility digestive enzymes, also proteins, are themselves susceptible to degradation by actinidin. Salivary amylase and gastric lipase are exposed
Belén Infanzón et al.
Biotechnology progress, 33(5), 1209-1217 (2017-09-09)
Previously isolated and characterized Pseudomonas lipases were immobilized in a low-cost MP-1000 support by a re-loading procedure that allowed a high activity per weight of support. Immobilized LipA, LipC, and LipCmut lipases, and commercial Novozym® 435 were tested for fatty
Shuqi Xing et al.
Frontiers in microbiology, 12, 633489-633489 (2021-03-30)
In this study, a sn-1, 3 extracellular lipases from Aspergillus niger GZUF36 (PEXANL1) was expressed in Pichia pastoris, characterized, and the predicted structural model was analyzed. The optimized culture conditions of P. pastoris showed that the highest lipase activity of
Amanda N Fletcher et al.
The journal of trauma and acute care surgery, 82(2), 338-344 (2017-01-21)
Fat embolism (FE) and the consequent FE syndrome occurring after trauma or surgery can lead to serious pulmonary injury, including ARDS and death. Current treatment of FE syndrome is limited to supportive therapy. We have shown in a rat model
Rakel Nyrén et al.
American journal of physiology. Renal physiology, 316(3), F558-F571 (2019-01-31)
Activity of lipoprotein lipase (LPL) is high in mouse kidney, but the reason is poorly understood. The aim was to characterize localization, regulation, and function of LPL in kidney of C57BL/6J mice. We found LPL mainly in proximal tubules, localized
Mathias Reisberg et al.
Journal of agricultural and food chemistry, 65(8), 1507-1517 (2017-01-26)
Ceramides (Cers) are major components of the outermost layer of the skin, the stratum corneum, and play a crucial role in permeability barrier functions. Alterations in Cer composition causing skin diseases are compensated with semisynthetic skin-identical Cers. Plants constitute new
Kanyaphat Bunchongprasert et al.
International journal of pharmaceutics, 561, 289-295 (2019-03-10)
This study aimed to investigate the following factors affecting the cytotoxicity of Capmul®MCM (C8/10MD) in self-emulsified nanoemulsions (SENs): concentration, triglycerides, and droplet size, and how these factors influence permeability of lipid droplets. Two triglycerides (C8T and C18T) and six formulations
Emma Lawless et al.
Pharmaceutical research, 32(5), 1817-1829 (2014-11-28)
Intestinal lymphatic transport of specific lipophilic drugs offers therapeutic advantages and maximises oral bioavailability. The aims of this study were; to compare intestinal lymphatic transport of a range of drugs and to investigate the influence of cyclosporine A on the
Saori Matsuo et al.
Toxicologic pathology, 42(8), 1174-1187 (2014-05-28)
Medulloblastomas (MBs) are thought to be derived from granular cell precursors in the external granular layer (EGL) of the developing cerebellum. Heterozygous patched1 (Ptch1) knockout mice develop MBs that resemble those in humans when the sonic hedgehog (Shh) signaling pathway
Yun Yang et al.
Pharmaceutical research, 35(7), 134-134 (2018-05-08)
Spherical reconstituted high density lipoprotein (rHDL) can target atherosclerotic lesions by the very low density lipoprotein (VLDL) receptor, which is seldom expressed in liver. By promoting this pathway, the targeting efficiency was hyphothesized to be improved due to avoiding undesired
Lan Yang et al.
Nanoscale, 12(28), 15222-15235 (2020-07-09)
The improvement and maintenance of enzymatic activities represent major challenges. However, to address these we developed novel biomimetic polysaccharide hyaluronan (Hn)-cloaked lipidic nanovesicles (BHLN) and microassemblies (BHLNM) as enzyme carriers that function by entrapping enzymes in the core or by
Younes Mohamed Ismail Hani et al.
Aquatic toxicology (Amsterdam, Netherlands), 199, 252-262 (2018-04-21)
The development of predictive, sensitive and reliable biomarkers is of crucial importance for aquatic biomonitoring to assess the effects of chemical substances on aquatic organisms, especially when it comes to combined effects with other stressors (e.g. temperature). The first purpose
Aisha Rafique et al.
International journal of nanomedicine, 14, 2829-2846 (2019-05-23)
Vitamin D3 possesses anti-inflammatory and modulatory properties in addition to its role in calcium and phosphate homeostasis. Upon activation, macrophages (M) can initiate and sustain pro-inflammatory cytokine production in inflammatory disorders and play a pathogenic role in certain cancers. The
Mst Ruhina Margia Khanam et al.
Chemosphere, 175, 200-209 (2017-02-22)
The present research investigated the effect of diuron on sinking rate and the physiochemical changes in two marine diatoms, Thalassiosira pseudonana (single-celled species) and Skeletonema marinoi-dohrnii complex (chain-forming species). The results revealed that the sinking rate of both diatoms exposed
Bat-Chen Cohen et al.
PloS one, 10(3), e0121645-e0121645 (2015-03-11)
Milk fat globule size is determined by the size of its precursors-intracellular lipid droplets-and is tightly associated with its composition. We examined the relationship between phospholipid composition of mammary epithelial cells and the size of both intracellular and secreted milk
Sandrina Lampis et al.
Colloids and surfaces. B, Biointerfaces, 168, 35-42 (2018-03-17)
Lipid based formulations, endowed of long term stability as a result of the formation of lamellar liquid crystals, were prepared using the natural lipids lecithin and glycerol trioleate in water, and characterized using optical microscopy, SAXRD and NMR. The formulations
Ryota Matsushita et al.
Communications biology, 3(1), 170-170 (2020-04-09)
Organisms have evolved molecular mechanisms to ensure consistent and invariant phenotypes in the face of environmental fluctuations. Developmental homeostasis is determined by two factors: robustness, which buffers against environmental variations; and developmental stability, which buffers against intrinsic random variations. However
Xuejie Guo et al.
BMC plant biology, 17(1), 48-48 (2017-02-23)
Oil in the form of triacylglycerols (TAGs) is quantitatively the most important storage form of energy for eukaryotic cells. Diacylglycerol acyltransferase (DGAT) is considered the rate-limiting enzyme for TAG accumulation. Chlorella, a unicellular eukaryotic green alga, has attracted much attention
Xin Wang et al.
International journal of biological macromolecules, 169, 239-250 (2020-12-22)
In this study, SBA-15 was modified by halogen & haloalkanes and later used to immobilize lipases. The hydrolysis activity and the glycerolysis performance of the immobilized lipases was carefully studied. Highest activity of the immobilized Candida antarctica lipase B (CALB)
M R Infantes-Garcia et al.
Food chemistry, 326, 126895-126895 (2020-05-22)
This investigation reports the effect of droplet size behavior on the overall lipolysis profile and molecular lipolysis mechanisms under in vitro gastric conditions. O/W emulsions (5% triolein, 1% sodium taurodeoxycholate) with different initial droplet sizes (fine: 0.58 μm; medium: 1.82 μm; and
Shan Hua et al.
Chemosphere, 177, 65-76 (2017-03-12)
Organochlorine pesticides (OCPs) in sediment were a potential damage for humans and ecosystems. The aim of this work was to determine the effectiveness of carbon materials remedy hexachlorocyclohexane (HCH) and dichlorodiphenyltrichloroethanes (DDTs) in sediment. Two different carbon materials including activated
Marielle Margier et al.
Molecular nutrition & food research, 62(11), e1800185-e1800185 (2018-04-19)
Food matrix is generally believed to alter carotenoid bioavailability, but its effect on xanthophylls is usually limited. This study thus aims to decipher the digestion-absorption process of lutein in the presence or not of a food matrix. Lutein transfer to
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