• Home
  • Search Results
  • Irreversible aggregation of alternating tetra-block-like amphiphile in water.

Irreversible aggregation of alternating tetra-block-like amphiphile in water.

PloS one (2018-08-28)
Shota Konno, Taisuke Banno, Hideaki Takagi, Satoshi Honda, Taro Toyota

As a frontier topic of soft condensed matter physics, irreversible aggregation has drawn attention for a better understanding of the complex behavior of biomaterials. In this study, we have described the synthesis of an artificial amphiphilic molecule, an alternating tetra-block-like amphiphile, which was able to diversify its aggregate structure in water. The aggregated state of its aqueous dispersion was obtained by slow evaporation of the organic solvent at room temperature, and it collapsed irreversibly at ~ 50°C. By using a cryo-transmission electron microscope and a differential scanning calorimeter, it was revealed that two types of molecular nanostructures were formed and developed into submicro- and micrometer-sized fibrils in the aggregated material.

Product Number
Product Description

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide, ≥97.0% (T)
11-Azido-3,6,9-trioxaundecan-1-amine, technical, ≥90% (GC)
Tetraethyleneglycol monomethyl ether, technical grade
5-(N,N-Dimethyl)amiloride hydrochloride
10-Undecynoic acid, 95%