IDH1 mutations in gliomas: when an enzyme loses its grip.

Cancer cell (2010-02-05)
Christian Frezza, Daniel A Tennant, Eyal Gottlieb

The growing interest in cancer metabolism is best demonstrated by the rapid progress made in studying isocitrate dehydrogenase (IDH) mutations since their discovery just over a year ago. In a recent study published in Nature, Dang et al. identified 2-hydroxyglutarate as a product of tumor-associated IDH mutants with potential oncogenic activities.

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Product Description

L-α-Hydroxyglutaric acid disodium salt, ≥98.0% (GC)
Anti-IDH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
L-α-Hydroxyglutaric acid disodium salt, analytical standard

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