Antitubercular constituents from the stem wood of Cinnamomum kotoense.

Journal of natural products (2005-09-27)
Fu-Chi Chen, Chien-Fang Peng, Ian-Lih Tsai, Ih-Sheng Chen
ABSTRACT

Five new compounds, kotolactone A (1), kotolactone B (2), secokotomolide (3), kotodiol (4), and 2-acetyl-5-dodecylfuran (5), and 36 known compounds have been isolated from the stem wood of Cinnamomum kotoense. The structures of these new compounds were determined by means of spectroscopic analysis. The known butanolides, isoobtusilactone A (6) and lincomolide B (7), showed in vitro antitubercular activities with MIC values of 22.48 and 10.16 microM, respectively, against Mycobacterium tuberculosis 90-221387.

MATERIALS
Product Number
Brand
Product Description

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Benzoic acid, ACS reagent, ≥99.5%
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Mettler-Toledo Calibration substance ME 18555, Benzoic acid, analytical standard, for the calibration of the thermosystem 900, traceable to primary standards (LGC)
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Lauric acid, ≥98%, FCC, FG
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3,4-Dihydroxybenzoic acid, ≥97.0% (T)
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Vanillin, ≥97%, FCC, FG
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Benzoic acid, ≥99.5%, FCC, FG
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Lauric acid, natural, ≥98%, FCC, FG
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Dodecanoic acid, 98%
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Vanillin, natural, ≥97%, FCC, FG
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Rifampicin, suitable for plant cell culture, BioReagent, ≥97% (HPLC), crystalline
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Benzoic acid, puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99.9% (alkalimetric)
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Dodecanoic acid, ≥99% (GC/titration)
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Mettler-Toledo Calibration substance ME 51143093, Vanillin, traceable to primary standards (LGC)
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Benzoic acid, ReagentPlus®, 99%
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Benzoic acid, meets analytical specification of Ph. Eur., BP, USP, FCC, E210, 99.5-100.5% (alkalimetric)
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Benzoic acid, Standard for quantitative NMR, TraceCERT®
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Dodecanoic acid, analytical standard
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4-Hydroxybenzaldehyde, ≥97%, FG
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Benzoic acid, certified reference material for titrimetry, certified by BAM, ≥99.5%
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Benzoic acid, purified by sublimation, ≥99%
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4-Hydroxybenzaldehyde, ≥95.0% (HPLC)
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