Melanin synthesis inhibitors from Lespedeza cyrtobotrya.

Journal of natural products (2008-12-24)
Maya Mori-Hongo, Hiromi Yamaguchi, Tsutomu Warashina, Toshio Miyase
ABSTRACT

From the roots of Lespedeza cyrtobotrya, 45 flavonoids were isolated along with 20 new and 25 known compounds. Lipophilic flavonoids 2, 3, 7, 9, 11, 28, 30, and 39 exhibited strong inhibitory activities on melanin synthesis in normal human epidermal melanocytes.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Hydroquinone, ReagentPlus®, ≥99%
Sigma-Aldrich
Genistein, synthetic, ≥98% (HPLC), powder
Sigma-Aldrich
Hydroquinone, ReagentPlus®, 99%
Sigma-Aldrich
Hydroquinone, meets USP testing specifications
Sigma-Aldrich
Genistein, from Glycine max (soybean), ~98% (HPLC)

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