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  • Anaerobic production of alginate by Pseudomonas aeruginosa: alginate restricts diffusion of oxygen.

Anaerobic production of alginate by Pseudomonas aeruginosa: alginate restricts diffusion of oxygen.

Journal of bacteriology (1996-12-01)
D J Hassett
ABSTRACT

Pseudomonas aeruginosa produced alginate and elevated algD (encoding GDPmannose 6-dehydrogenase) transcription under strict anaerobic conditions, especially when using nitrate as a terminal electron acceptor. Purified alginate added to bacterial suspensions caused a decrease in growth, suggesting that alginate contributes to oxygen limitation for the organism and likely for patients afflicted with the inherited autosomal disease cystic fibrosis.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Anti-Pseudomonas aeruginosa Exotoxin A antibody, Mouse monoclonal, clone EXO-68, purified from hybridoma cell culture