Helical chiral pyridine N-oxides: a new family of asymmetric catalysts.

Chemistry (Weinheim an der Bergstrasse, Germany) (2009-07-07)
Jinshui Chen, Norito Takenaka
ABSTRACT

Optically active chiral alkyl chlorides are valuable compounds because of their bioactivity and versatile synthetic utility. Accordingly, the ring opening of epoxides with a chloride nucleophile stands as an important goal in asymmetric catalysis. We describe herein recent advances in the design and development of chiral pyridine N-oxide catalysts for the enantioselective synthesis of chlorohydrins.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Pyridine N-oxide, 95%

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