Interaction of C(60) fullerene with lipids.

Chemistry and physics of lipids (2010-03-27)
Franco Cataldo
ABSTRACT

Unsaturated lipids when exposed to air at room temperature undergo a slow autoxidation. When fullerene C(60) was dissolved in selected lipids (ethyl oleate, ethyl linoleate, linseed oil and castor oil) the spectrophotometric analysis shows that the oxidation is concentrated to C(60) which is converted to an epoxide C(60)O. Thus, fullerene C(60) displays antioxidant activity not only when dissolved in unsaturated lipids but also, more generally, when dissolved in unsaturated solvents subjected to autoxidation like, for example, in cyclohexene. The behaviour of C(60) in ethyl oleate has been compared with that of the known antioxidant TMPPD (N,N',N,N,'-tetramethyl-p-phenylenediamine) in ethyl oleate. The mechanism of the antioxidant action of C(60) in lipids has been proposed. The kinetics of C(60) oxidation in lipids was determined spectrophotometrically both at room temperature in the dark and under UV irradiation. The oxidized products derived from C(60) photo-oxidation in lipids have been identified.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Ethyl oleate, 98%
Sigma-Aldrich
Ethyl linoleate, ≥99%
Sigma-Aldrich
Ethyl oleate, tested according to Ph. Eur.
Sigma-Aldrich
Ethyl oleate, natural, ≥85%
Sigma-Aldrich
Ethyl linoleate, technical, ≥65% (GC)
Sigma-Aldrich
Ethyl oleate, technical grade, 70%