• Home
  • Search Results
  • Noncovalent immobilization of ionic-tagged box-Cu(OAc)2 complex and its application in asymmetric Henry reaction.

Noncovalent immobilization of ionic-tagged box-Cu(OAc)2 complex and its application in asymmetric Henry reaction.

Chirality (2012-09-25)
Zhi-Huai Li, Zhi-Ming Zhou, Xiao-Yan Hao, Jun Zhang, Xiao Dong, Ying-Qiang Liu
ABSTRACT

Immobilized Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding by SBA-15 was applied to asymmetric Henry reaction, and good enantioselectivities were obtained (up to 83% ee) between 2-methoxybenzaldehyde and CH(3)NO(2) in isopropyl alcohol (iPrOH). The catalyst could be reused seven times without any obvious loss in enantioselectivity. For the first time, this facile and clean immobilization method is applied to the use of bis(oxazolines) complexes.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Benzaldehyde, ReagentPlus®, ≥99%
Sigma-Aldrich
Benzaldehyde, purified by redistillation, ≥99.5%
Sigma-Aldrich
Nitromethane, ACS reagent, ≥95%
Supelco
Benzaldehyde, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Benzaldehyde, analytical standard
Sigma-Aldrich
Nitromethane, ReagentPlus®, ≥99.0%
Sigma-Aldrich
2-Methoxybenzaldehyde, 98%
Sigma-Aldrich
Nitromethane, puriss., absolute, over molecular sieve (H2O ≤0.01%), ≥98.5% (GC)
Sigma-Aldrich
Benzaldehyde, puriss. p.a., ≥99.0% (GC)
Sigma-Aldrich
Benzaldehyde, natural, FCC, FG
Sigma-Aldrich
Benzaldehyde, ≥98%, FG, FCC
Sigma-Aldrich
Nitromethane, suitable for HPLC, ≥96%
Supelco
Nitromethane, analytical standard
Benzaldehyde, European Pharmacopoeia (EP) Reference Standard

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.