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Antibacterial strategies from the sea: polymer-bound cl-catechols for prevention of biofilm formation.

Advanced materials (Deerfield Beach, Fla.) (2012-11-10)
Luis García-Fernández, Jiaxi Cui, Cristina Serrano, Zahid Shafiq, Radu A Gropeanu, Verónica San Miguel, Jagoba Iturri Ramos, Miao Wang, Gunther K Auernhammer, Sandra Ritz, Ali A Golriz, Rüdiger Berger, Manfred Wagner, Aránzazu del Campo
ABSTRACT

Inspired by the amino acid 2-chloro-4,5-dihydroxyphenylalanine (Cl-DOPA), present in the composition of the proteinaceous glue of the sandcastle worm Phragmatopoma californica, a simple strategy is presented to confer antifouling properties to polymer surfaces using (but not releasing) a bioinspired biocide. Cl-Dopamine is used to functionalize polymer materials and hydrogel films easily, to prevent biofilm formation on them.

MATERIALS
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Brand
Product Description

Sigma-Aldrich
3,4-Dihydroxy-DL-phenylalanine