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Peptide directed transmembrane transport and nuclear localization of Ru(II) polypyridyl complexes in mammalian cells.

Chemical communications (Cambridge, England) (2013-02-26)
Lorraine Blackmore, Roisin Moriarty, Ciaran Dolan, Kellie Adamson, Robert J Forster, Marc Devocelle, Tia E Keyes
ABSTRACT

The targeted delivery of luminescent Ru(II) polypyridyl complexes to the nucleus of live mammalian cells by a Nuclear Localisation Signal (NLS) peptide; NF-κB is demonstrated.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Ruthenium, powder, 99.99% trace metals basis
Sigma-Aldrich
Ruthenium, powder, −200 mesh, 99.9% trace metals basis
Sigma-Aldrich
Ruthenium black
Sigma-Aldrich
Ruthenium, sponge, −100 mesh, 99.9% trace metals basis

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