A novel carbon isotope biomarker for dietary sugar.

The Journal of nutrition (2013-04-26)
Dale A Schoeller
ABSTRACT

Light element isotope signatures have been used to study food webs in many ecological niches, including those of ancient humans, but to a far lesser extent in modern humans. A recent paper presented results from a pilot study testing the utility of carbon isotope ratio analysis of alanine to measure an individual's sugar intake in the United States. A strong correlation was found between the enrichment of (13)C in alanine and sugar-sweetened beverage consumption. This candidate biomarker of sugar consumption deserves further consideration as an objective marker for use in the study of the relationship between sugar intake and health.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
L-Alanine, ≥98% (TLC)
Sigma-Aldrich
L-Alanine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%
Sigma-Aldrich
L-Alanine, BioUltra, ≥99.5% (NT)
Supelco
L-Alanine, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
L-Alanine, ≥99%
Sigma-Aldrich
L-Alanine, ≥99.0% (NT)
Alanine, European Pharmacopoeia (EP) Reference Standard
Supelco
L-Alanine, certified reference material, TraceCERT®
Sigma-Aldrich
L-Alanine-12C3, 99.9 atom % 12C