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Pulmonary renal syndrome in a case of Wegener's granulomatosis.

The Indian journal of chest diseases & allied sciences (2013-06-27)
Susmita Kundu, Swapnendu Misra, Ranjit Kumar Halder, Arpita Roychowdhury
ABSTRACT

We report a case of a 42-year-old patient who presented with Wegener's granulomatosis complicated by pulmonary renal syndrome, i.e., diffuse alveolar haemorrhage and rapidly progressive crescentic glomerulonephritis. The patient was treated with plasmapheresis and immunosuppressive drugs--intravenous cyclophosphamide and methyl prednisolone. The clinical, haematological and biochemical parameters improved substantially and remission is achieved.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
6α-Methylprednisolone, ≥98%
Methylprednisolone, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
Cyclophosphamide monohydrate, bulk package
Sigma-Aldrich
Cyclophosphamide monohydrate, ISOPAC®
Supelco
6α-Methylprednisolone, VETRANAL®, analytical standard