A simple and rapid stain for copper in liver tissue.

Annals of diagnostic pathology (1998-12-10)
P Emanuele, Z D Goodman
ABSTRACT

We report a modified copper stain that can be completed in 2 hours, rather than overnight, which is required for other stains. This is useful in the diagnosis of chronic cholestatic syndromes, Wilson's disease, Indian childhood cirrhosis, and other conditions associated with copper retention.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
5-(4-Dimethylaminobenzylidene)rhodanine, 97%
Supelco
5-(4-Dimethylaminobenzylidene)rhodanine, for TLC derivatization, ≥98.0%