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Commentary to the article "Human skin penetration of the major components of Australian tea tree oil applied in its pure form and as a 20% solution in vitro".

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V (2008-02-19)
Krzysztof Cal
ABSTRACT

This note summarises recent studies on skin penetration of terpinen-4-ol, which is the main component of tea tree oil [S.E. Cross, M. Russell, I. Southwell, M.S. Roberts, Human skin penetration of the major components of Australian tea tree oil applied in its pure form and as a 20% solution in vitro, Eur. J. Pharm. Biopharm. doi: 10.1016/j.ejpb.2007.10.002 (in press)]. The influence of different experimental models on obtained skin penetration results is discussed.

MATERIALS
Product Number
Brand
Product Description

Terpinen 4-ol, primary reference standard
Sigma-Aldrich
4-Carvomenthenol, ≥95%, FCC, FG
Sigma-Aldrich
4-Carvomenthenol, natural, ≥95%, FG