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Microbial metabolism of quinoline and related compounds. VI. Degradation of quinaldine by Arthrobacter sp.

Biological chemistry Hoppe-Seyler (1990-10-01)
H K Hund, A de Beyer, F Lingens
ABSTRACT

Quinaldine catabolism was investigated with the bacterial strain Arthrobacter sp., which is able to grow aerobically in a mineral salt medium with quinaldine as sole source of carbon, nitrogen and energy. The following degradation products of quinaldine were isolated from the culture fluid and identified: 1H-4-oxoquinaldine, N-acetylisatic acid, N-acetylanthranilic acid, anthranilic acid, 3-hydroxy-N-acetylanthranilic acid and catechol. 3-Hydroxy-N-acetylanthranilic acid was not further metabolized by this organism. A degradation pathway is proposed.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
N-Acetylanthranilic acid, 99%