[Study on chemical constituents of Artemisia sphaerocephala].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (2012-06-29)
Jie Zhang, Linxi Li, Xiuhua Liu, Yong Wang, Dongbao Zhao
ABSTRACT

Further study on the chemical constituents of Artemisia sphaerocephala led to the isolation of fifteen compounds. These compounds were isolated and purified by repeated column chromatography on silica gel and Sephadex LH-20. Their structures were determined by physicochemical properties and spectral data analysis. These compounds were identified as 5-hydroxy-7,4'-dimethoxyflavanone (1), 5-hydroxy-7, 4'-dimethoxyflavone (2), 5-hydroxy-7, 4'-dimethoxyflavanonol (3), 5,3'-dihydroxy-7, 4'-dimethoxyflavanone (4), 5,7-dihydroxy-6,4'-dimethoxyflavone (5), isosakuranetin (6), hesperetin (7), navingenin (8), acacetin (9), chrysoeroil (10), 5,7-dihydroxy-4'-methoxyflavone-6,8-di-C- -glucopyranoside (11), didymin (12), acacetin-7-O-rutinoside (13), piceine (14), and capillarin (15). Compounds 1-3, 5, 7, 8, 10-15 were isolated from this plant for the first time.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Acacetin, ≥97.0% (HPLC)