Vanadium-catalyzed enantioselective Friedel-Crafts-type reactions.

Dalton transactions (Cambridge, England : 2003) (2012-10-30)
Shinobu Takizawa, Fernando Arteaga Arteaga, Yasushi Yoshida, Junpei Kodera, Yoshihiro Nagata, Hiroaki Sasai
ABSTRACT

Vanadium-mediated enantioselective Friedel-Crafts (FC)-type reactions were established using the dinuclear vanadium complex (R(a),S,S)-1a. The vanadium complex promoted the FC-type reaction of imines with 2-naphthols or indoles to give corresponding adducts with high enantioselectivities.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
2-Naphthol, 99%
Sigma-Aldrich
Vanadium, powder, −325 mesh, 99.5% trace metals basis
Sigma-Aldrich
2-Naphthol, 98%
Sigma-Aldrich
Vanadium, foil, thickness 0.127 mm, 99.7% trace metals basis
Sigma-Aldrich
2-Naphthol, fluorescence indicator, ≥99.0%
Sigma-Aldrich
2-Naphthol, BioXtra, ≥99.0% (GC)
Sigma-Aldrich
Vanadium, foil, thickness 0.25 mm, 99.7% trace metals basis
Sigma-Aldrich
Vanadium, rod, diam. 6.2 mm, 99.7% trace metals basis
Sigma-Aldrich
Vanadium, turnings, 99.7% trace metals basis
Sigma-Aldrich
Vanadium, foil, thickness 0.5 mm, 99.7% trace metals basis