• Home
  • Search Results
  • Oxidation of aromatic N-heterocyclic compounds to N-oxides by Verticillium sp. GF39 cells.

Oxidation of aromatic N-heterocyclic compounds to N-oxides by Verticillium sp. GF39 cells.

Journal of bioscience and bioengineering (2013-01-08)
Koichi Mitsukura, Masafumi Hayashi, Toyokazu Yoshida, Toru Nagasawa
ABSTRACT

Verticillium sp. GF39, catalyzing the oxidation of 1-methylisoquinoline to 1-methylisoquinoline N-oxide, was found to be the highest N-oxide producer. Under the optimized reaction conditions, the whole cells of Verticillium sp. GF39 formed 5 mM 1-methylisoquinoline N-oxide from 1-methylisoquinoline with a molar conversion yield of 100% after a 10-h incubation at 20°C. The whole cells also acted on pyridine, 2-methylpyridine, quinoline and isoquinoline and formed the corresponding N-oxides.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
1-Methylisoquinoline, 97%

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.