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An overview of highly optically pure chloramphenicol bases: applications and modifications.

Mini reviews in medicinal chemistry (2009-11-26)
Kanghui Yang, Hao Fang, Jianzhi Gong, Li Su, Wenfang Xu
ABSTRACT

Chloramphenicol (CAP) is a widely used broad-spectrum antibiotic. As the precursor of CAP, chloramphenicol bases are stereochemically pure agents and could be used as resolution agents, chiral catalysts and so on. This review summarizes these applications and discusses the structural modifications of chloramphenicol bases.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Chloramphenicol, ≥98% (HPLC)
Sigma-Aldrich
Chloramphenicol, BioReagent, suitable for plant cell culture
Supelco
Chloramphenicol, VETRANAL®, analytical standard
Sigma-Aldrich
Chloramphenicol, meets USP testing specifications
Sigma-Aldrich
Chloramphenicol, γ-irradiated
Chloramphenicol, European Pharmacopoeia (EP) Reference Standard