- Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA.
Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA.
Journal of inorganic biochemistry (2012-07-24)
A G Quiroga
PMID22819649
ABSTRACT
This focused review is devoted to our advances in developing trans platinum complexes as antitumoral complexes, in particular those bearing aliphatic amines. It includes some fundamental aspects of the understanding of non conventional metallodrug mechanism. The perspective is arranged by those fundamental aspects and within each section only the most successful examples have been included and also those in which clearly SAR's (structure activity relationships) have been observed.
MATERIALS
Product Number
Brand
Product Description
Platinum, foil, not light tested, 50x50mm, thickness 0.005mm, as rolled, 99.95%
Platinum, foil, 30x30mm, thickness 0.2mm, as rolled, 99.95%
Platinum, wire reel, 0.05m, diameter 0.8mm, annealed, may be used as one component of a thermocouple, 99.99%
Platinum, wire reel, 0.05m, diameter 0.6mm, as drawn, 99.99+%
Platinum, insulated wire, 5m, conductor diameter 0.05mm, insulation thickness 0.009mm, PTFE (polytetrafluoroethylene) insulation, 99.99%
Platinum, wire reel, 0.05m, diameter 1.0mm, annealed, may be used as one component of a thermocouple, 99.99%
Platinum, foil, 15x15mm, thickness 0.2mm, as rolled, 99.95%
Platinum, tube, 500mm, outside diameter 1.2mm, inside diameter 1.0mm, wall thickness 0.1mm, as drawn, 99.95%
Platinum, foil, 25x25mm, thickness 0.125mm, as rolled, 99.95%
Platinum, foil, 50x50mm, thickness 0.125mm, as rolled, 99.99+%
Platinum, tube, 50mm, outside diameter 1.0mm, inside diameter 0.8mm, wall thickness 0.1mm, as drawn, 99.95%
Platinum, foil, 0.1m coil, thickness 0.15mm, coil width .9mm, as rolled, 99.99%
Platinum, wire reel, 0.05m, diameter 1.0mm, as drawn, 99.99+%
Platinum, foil, 0.05m coil, thickness 0.029mm, coil width .34mm, annealed, 99.99%
Platinum, wire reel, 0.05m, diameter 0.25mm, as drawn, 99.998%
Platinum, wire reel, 0.05m, diameter 0.20mm, annealed, may be used as one component of a thermocouple, 99.99%
Platinum, foil, 4mm disks, thickness 0.05mm, as rolled, 99.95%