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The methenamine misunderstanding in the therapy of phosgene poisoning.

Archives of toxicology (1980-12-01)
W F Diller
ABSTRACT

A thorough analysis of the pertinent literature leads to the conclusion that there is no justification for the use of methenamine (hexamethylene tetramin, Urotropin) for the therapy of phosgene poisoning.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Hexamethylenetetramine, ReagentPlus®, 99%
Sigma-Aldrich
Hexamethylenetetramine, ACS reagent, ≥99.0%
Sigma-Aldrich
Hexamethylenetetramine, meets analytical specification of Ph. Eur., BP, 99-100.5% (calc. to the dried substance)
Sigma-Aldrich
Hexamethylenetetramine, puriss. p.a., reag. Ph. Eur., ≥99.5% (calc. to the dried substance)
Methenamine, European Pharmacopoeia (EP) Reference Standard
Supelco
Hexamethylenetetramine
Sigma-Aldrich
Phosgene solution, 15 wt. % in toluene