Polyacrylamide-based glycoconjugates as tools in glycobiology.

Glycoconjugate journal (1999-01-09)
N V Bovin

This review describes the synthesis, physicochemical characteristics and application for studying carbohydrate-binding proteins of polyacrylamide (PAA) type neoglycoconjugates. An approach to the synthesis of conjugates based on the interaction of activated polyacrylic acid with omega-aminoalkyl glycosides has been developed. Both the molecules of Glyc-PAA and the conjugates bearing various labels and effectors, as well as sorbents, and glycosurfaces can be designed using this method. Examples of the application of the conjugates as tools for the study of lectins, antibodies, and glycosyltransferases in glycobiology, cytochemistry and histochemistry are described along with the prospects of the further development of the presented approach in glycotechnology and medicine.

Product Number
Product Description

Polyacrylamide, nonionic water-soluble polymer
Polyacrylamide, average Mn 150,000
Polyacrylamide, average Mn 40,000