Occurrence of carbamazepine and five metabolites in an urban aquifer.

Chemosphere (2014-02-25)
Anna Jurado, Rebeca López-Serna, Enric Vázquez-Suné, Jesus Carrera, Estanislao Pujades, Mira Petrovic, Damià Barceló
ABSTRACT

This paper deals with urban groundwater contaminated with carbamazepine (CBZ) and five of its human metabolites in Barcelona. Groundwater samples were accordingly collected in the aquifers of Poble Sec and Besòs River Delta. Higher concentrations and more compounds were found in the Besòs River Delta aquifer, which is recharged by a river contaminated with treated effluent from numerous treatment plants. By contrast, the urban area of Poble Sec presented lower concentrations and fewer compounds. The results showed that CBZ could be attenuated in the Poble Sec aquifer since concentrations in groundwater were lower than those evaluated from mixing of the recharge sources. Conversely, CBZ and its human metabolites were not removed under the reducing conditions of the Besòs River Delta aquifer probably because of the short residence time in this aquifer.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Carbamazepine, powder
Supelco
Carbamazepine, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Carbamazepine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
Supelco
Carbamazepine, analytical standard
Sigma-Aldrich
Carbamazepine, meets USP testing specifications
Carbamazepine, European Pharmacopoeia (EP) Reference Standard
USP
Carbamazepine, United States Pharmacopeia (USP) Reference Standard