• Home
  • Search Results
  • Increased chemopreventive effect by combining arctigenin, green tea polyphenol and curcumin in prostate and breast cancer cells.

Increased chemopreventive effect by combining arctigenin, green tea polyphenol and curcumin in prostate and breast cancer cells.

RSC advances (2014-09-23)
Piwen Wang, Bin Wang, Seyung Chung, Yanyuan Wu, Susanne M Henning, Jaydutt V Vadgama
ABSTRACT

The low bioavailability of most flavonoids limits their application as anti-carcinogenic agents in humans. A novel approach of treatment with a mixture of bioactive compounds that share molecular anti-carcinogenic targets may enhance the effect on these targets at low concentrations of individual compound, thereby overcoming the limitations of reduced bioavailability. We therefore investigated whether a combination of three natural products arctigenin (Arc), a novel anti-inflammatory lignan from the seeds of

MATERIALS
Product Number
Brand
Product Description

SAFC
BIS-TRIS
Sigma-Aldrich
Propidium iodide, ≥94.0% (HPLC)
Sigma-Aldrich
Propidium iodide solution, solution (1.0 mg/ml in water)
Sigma-Aldrich
BIS-TRIS, ≥98.0% (titration)
Sigma-Aldrich
(−)-Epigallocatechin gallate, ≥95%
Sigma-Aldrich
Propidium iodide, ≥94% (HPLC)
Sigma-Aldrich
(−)-Epigallocatechin gallate, ≥80% (HPLC), from green tea
Sigma-Aldrich
BIS-TRIS, BioXtra, ≥98.0% (titration)
Supelco
Epigallocatechin gallate, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
BIS-TRIS, BioUltra, ≥99.0% (NT)
Supelco
(−)-Epigallocatechin gallate, analytical standard
Sigma-Aldrich
BIS-TRIS, BioPerformance Certified, suitable for cell culture, suitable for insect cell culture, ≥98.0%
SAFC
BIS-TRIS
Epigallocatechin gallate, primary reference standard