Consistent analyte detection and quantification require reliable reagents, and not all biomarker kits are created equal. Our kits are rigorously tested using a range of verified methods to ensure optimized performance and lot-to-lot consistency. Providing the specificity, biological dynamic ranges, and sensitivity that you require, our versatile ELISAs, ultrasensitive SMC® assays, and MILLIPLEX® multiplex assays using Luminex® xMAP® technology deliver consistent performance, lot after lot. See the difference by choosing a platform with our biomarker kits to confidently deliver reproducible results.
When thinking about what immunoassay platform you need, there are some factors you should consider, including:
Researchers rely on commercial immunoassays to study biomarker expression in a wide variety of research applications. With recent technological advances pushing the limits of protein quantification in high sensitivity and multiplex analyte detection, we are committed to delivering the best possible immunoassays for your research needs. Whether you are using our industry-leading MILLIPLEX® multiplex panels to broadly survey multiple analytes, performing femtogram/mL biomarker analysis using the Single Molecule Counting (SMC®) ultrasensitive immunoassay platform, or examining single proteins with our tried-and-true ELISAs and radioimmunoassays (RIAs), you can confidently expect reliable measurements, a simplified user experience, and knowledgeable scientific partners to help drive your biomarker project from hypothesis to publication. Table 1 gives a breakdown of these different platforms.
Our immunoassay platforms offer many advantages including:
Our industry-leading MILLIPLEX® multiplex immunoassays based on Luminex® xMAP® technology offer simultaneous surveillance of multiple analytes. Features include:
Combined with the largest portfolio of multiplex biomarkers available, we provide you with the power of Luminex® xMAP® instrumentation, the most trusted, widely-used platform for biomarker screening and protein analysis. Choose between the xMAP® INTELLIFLEX®, FLEXMAP 3D®, or the Luminex® 200™ systems.
Learn more about MILLIPLEX® multiplex assays in our Overview of Luminex® Multiplex Assay Technology article.
For low-abundant biomarkers, our Single Molecule Counting (SMC®) kits and SMCxPRO® platform offer high sensitivity detection. Use it to explore previously undetectable analytes with measurements down to femtogram levels. SMC® technology provides maximum immunoassay performance while following an easy-to-follow workflow, similar to traditional ELISA technology. These assays are optimized for the SMCxPRO® platform, a complete fluidics-free system that provides sensitive quantification for both low and high levels of expression. This platform covers a broad range of research areas including:
Discover more about SMC® technology in our Overview of Ultrasensitive Immunoassay Technology article.
Quantify critical targets with ELISAs that combine the specificity of antibodies with the sensitivity of simple enzyme assays. Our manufacturing of highly verified, preconfigured ELISAs and RIAs is the gold standard, giving you the same accuracy and precision in every lot, backed by the same, unwavering technical support.
Specifically, our Conferma® ELISAs were engineered to increase data reproducibility by utilizing physiochemical analysis tools to confirm reagent similarity prior to assay manufacture. This growing product line currently offers Human IL-6, IL-8, MCP-1, and TNFα ELISAs.
Discover more about this process in our Conferma® ELISAs article.
All of these platforms can be used together to give you a complete picture of your research. The MILLIPLEX® multiplex platform can be used to screen biomarkers and find your biomarkers of interest. From there, you can perform targeted biomarker analysis with Conferma® ELISAs for routine biomarkers, or deeper analysis of selected biomarkers through the ultrasensitive SMC® platform.
We also offer additional tools to complete your immunoassay workflows.
Supporting all three platforms, our Belysa® Immunoassay Curve Fitting Software provides a user-friendly tool to ensure your methods are reproducible over time at the single assay level, over multiple plates, and over multiple lots. It is compatible with both Windows 10 and macOS (beta).
With Belysa® analysis software you can:
See how easy it is to use this software in our Belysa® software article.
Leverage our immunoassay expertise to create your custom biomarker assay solution. We follow a milestone-based process to develop the “Fit for Purpose” assay you need. From beginning to end, your assay development journey will be an interactive, iterative process as you work closely with our team to meet your research goals.
When you do not have the time or resources to develop your own assay, our Custom Assay Development & Innovation team can help accelerate projects from the discovery stage to clinical trials with:
Experience enhanced flexibility with services to:
Discover more about these services on our Custom Assay page.
Complete your workflows with ancillary equipment such as plate washers and ELISA reading equipment in partnership with BioTek® instruments.
Download our Analyte Quarterly brochure for a full listing of all our products.
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