HomeMILLIPLEX® Multiplex for Luminex® ImmunoassaysMultiplexing Metabolic Syndrome Biomarkers

See the Full Metabolic Syndrome Picture By Multiplexing Metabolic Biomarkers

Metabolic syndrome involves a combination of serious health issues such as diabetes and obesity. Multiplex immunoassays are critical in this research because they provide a full picture of the different conditions related to metabolic syndrome as well as save the researcher valuable time and sample volume.

What is Metabolic Syndrome?

Metabolic syndrome is a state of low-grade inflammation that contributes to a combination of conditions that impact metabolism and hormones. Obesity, diabetes, and associated conditions, under the umbrella of metabolic syndrome, are urgent health issues. Key features of the metabolic syndrome include:

  • Insulin resistance
  • Glucose intolerance
  • Hypertension
  • Dyslipidemia
  • Central obesity
  • Neuropathy

These symptoms are risk factors for atherosclerosis, coronary heart disease, type 2 diabetes, kidney disease, and even premature death. Adults with metabolic syndrome show inflammation, which may be linked to metabolism via dysregulated adipocyte production of pro- and anti-inflammatory factors.

Biomarkers for Metabolic Syndrome

Biomarkers for metabolic syndrome include cytokines, acute phase proteins, diabetes, and obesity-related hormones, as well as endocrine biomarkers. The expanding portfolio of MILLIPLEX® multiplex metabolic assays helps detect endocrine biomarkers, hormones, insulin-like growth factors, and binding proteins, myokines, bone metabolism biomarkers, and more, to advance your metabolic syndrome research.

Multiplexing Metabolic Syndrome Biomarkers

Multiplexing metabolic syndrome biomarkers allow researchers to gain a complete picture of the various conditions associated with metabolic syndrome. The following graphs in Figure 1 show data for selected analytes of human plasma/serum samples assayed using the MILLIPLEX® Human Metabolic Hormone Panel V3.

MILLIPLEX® Multiplex Analysis of Metabolic Syndrome Biomarkers: C-Peptide, GIP
MILLIPLEX® Multiplex Analysis of Metabolic Syndrome Biomarkers: Leptin, Pancreatic Polypeptide

Figure 1. Two groups of non-diabetic control serum/plasma, fasted (n=14) and post-fasted (n=14), were sourced commercially and run according to protocol in the Human Metabolic Hormone Panel V3 (Cat. No. HMH3-34K).

Related MILLIPLEX® Assays

Explore our MILLIPLEX® multiplex assays for metabolism and endocrine biomarkers.

Diabetic, Metabolic, and Gut Hormones

Gut hormones regulate gut motility and secretion, pancreatic islet hormone secretion, food intake, and energy expenditure.



Hormones called adipokines regulate appetite and energy balance, insulin sensitivity, and lipid metabolism.


Bone and Myokine Biomarkers

Bone and myokine biomarkers include myostatin, irisin, oncostatin M, osteocalcin, and more.


Hormones of Reproduction, Development, and Homeostasis

Pituitary, thyroid, stress, and reproductive hormones relate to the management of the reproduction, development, and homeostasis systems in the body.


For Research Use Only. Not For Use In Diagnostic Procedures.

If you cannot find the assay you are looking for, we also offer custom assay services to help you multiplex it your way and develop the right assay for your research.

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