Growth Factors and Cytokines for Cell Culture - Selection Guide

Growth factors and cytokines are responsible for mediating communication between cells and regulating cellular functions in vitro and in vivo. In cell culture, these important media supplements are often classified into “families” based off their function or the cell type that they regulate. Our extensive collection of growth factors and cytokines can be used to supplement cellular media, as well as for target identification and drug development. The tables below can be used to guide growth factor and cytokine selection for your cell culture needs.

Growth Factors and Cytokines Applications

Cell Health

Area of research	Growth Factor/Cytokine	E. coli-Expressed	Animal Component-Free Option	HEK-Expressed, Xeno-Free
Proliferation	EGF	E9644	SRP3027	E1235
Growth	FGF-2	F0291 SRP4037	GF003AF SRP3043
Apoptosis	TNF-alpha	T6674 GF023	SRP3177	H8916
Protein synthesis	IGF-1	I3769 GF306	SRP3069

Tissue Repair

Area of research	Growth Factor/Cytokine	E. coli-Expressed	Animal Component-Free Option	HEK-Expressed, Xeno-Free
Migration	TGF-beta1	T7039		H8541
Angiogenesis	PlGF	P1588 SRP4739	SRP3145
Epithelial cell differentiation	KGF	K1757	SRP3100	H6666
ECM production	PDGF-AA	P3076 GF142	SRP3268
	PDGF-BB	P4306 P3201 GF149	SRP3138

Stem Cell Biology

Area of research	Growth Factor/Cytokine	E. coli-Expressed	Animal Component-Free Option	HEK-Expressed, Xeno-Free
Stem cell maintenance	LIF	L5283 LIF1010 LIF1050 LIF1005	SRP3316 L9545 GF342
Vascularization	VEGF	V7259 01-185	SRP3182
Neuronal survival	beta NGF	SRP3015	SRP3018 GF307	N5415 H9666 GF401
Neurite outgrowth	BDNF	B3795 SRP3014	GF301
Neuronal growth	GDNF	G1777	SRP3309 GF322
Mast cell development	SCF	S7901 GF021	SRP3151 GF312	H8416
Bone & cartilage development	BMP-2	B3555 B1814 GF166	SRP3326 GF319	H4791 SRP6155
	BMP-4	SRP3016 GF167	GF302	H4916 SRP6156
Thrombopoiesis	TPO	T1568	SRP3178 GF347	GF443
Erythropoiesis	EPO			E5546 SRP6158 H5166

Inflammation & Immune Responses

Area of research	Growth Factor/Cytokine	E. coli-Expressed	Animal Component-Free Option	HEK-Expressed, Xeno-Free
Immune cell activation & proliferation	IL-1beta	I2778	SRP3083	H6291 GF418-MG
Cytokine production	IL-2	I2644	SRP3085	H7041 GF423
Metabolic regulation	IL-4	I4269 SRP4137	SRP3093 GF337	H7291
Neuroinflammation	IL-6	I1395	SRP3096 GF338	H7416 SCU0001
Viral pathogen response	IFN-gamma	I3265 IF002	SRP3058 GF305	I17001

Innate Immunity

Area of research	Growth Factor/Cytokine	E. coli-Expressed	Animal Component-Free Option	HEK-Expressed, Xeno-Free
Granulocyte funtion & neutrophil production	G-CSF	G0407	SRP3263 GF303
Macrophage function & dendritic cell development	GM-CSF	G5035	SRP3050 GF304	H5666
Proliferation & differentiation of macrophages	M-CSF	M6518	SRP3110	H6916