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ARFGAP3

ADP-ribosylation factor GTPase activating protein 3

Sinónimos:
ARFGAP1
Especie:
ID UniProtKB:
ID del gen:
  • Human(26286) Summary: The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008]
  • Mouse(66251) ADP-ribosylation factor GTPase activating protein 3
  • Rat(503165) ADP-ribosylation factor GTPase activating protein 3
  • sheep(101115447) ADP-ribosylation factor GTPase activating protein 3
  • cow(532778) ADP-ribosylation factor GTPase activating protein 3
  • naked mole-rat(101717408) ADP-ribosylation factor GTPase activating protein 3
  • Zebrafish(402889) ADP-ribosylation factor GTPase activating protein 3
  • fruit fly(40487) ADP-ribosylation factor GTPase activating protein 3
  • domestic cat(101091637) ADP-ribosylation factor GTPase activating protein 3
  • dog(474477) ADP-ribosylation factor GTPase activating protein 3
  • chicken(418224) ADP-ribosylation factor GTPase activating protein 3
  • domestic guinea pig(100725575) ADP-ribosylation factor GTPase activating protein 3

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-ARFGAP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human ARFGAP3,
Especie
human
MISSION® esiRNA, targeting mouse Arfgap3,
Especie
mouse