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MilliporeSigma

CRYBB3

crystallin, beta B3

Sinónimos:
CATCN2, CRYB3, CTRCT22
Especie:
ID UniProtKB:
ID del gen:
  • Human(1417) Summary: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B2. Mutations in this gene result in cataract congenital nuclear autosomal recessive type 2. [provided by RefSeq, Feb 2013]
  • Mouse(12962) crystallin, beta B3
  • Rat(64349) crystallin, beta B3
  • Zebrafish(553184) crystallin, beta B3
  • domestic guinea pig(100306963) crystallin, beta B3
  • naked mole-rat(101709702) crystallin, beta B3
  • domestic cat(101082953) crystallin, beta B3
  • cow(282206) crystallin, beta B3
  • sheep(780513) crystallin, beta B3
  • chicken(396108) crystallin, beta B3
  • dog(790954) crystallin, beta B3

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-CRYBB3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Crybb3,
Especie
mouse