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SCN7A

sodium channel, voltage-gated, type VII, alpha subunit

Sinónimos:
NaG, Nav2.1, Nav2.2, SCN6A
Especie:
ID UniProtKB:
ID del gen:
  • Human(6332) Summary: This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011]
  • Mouse(20272) sodium channel, voltage-gated, type VII, alpha
  • Rat(64155) sodium channel, voltage-gated, type VII, alpha
  • naked mole-rat(101711842) sodium channel, voltage-gated, type VII, alpha subunit
  • domestic guinea pig(100715553) sodium channel, voltage-gated, type VII, alpha subunit
  • dog(488382) sodium channel, voltage-gated, type VII, alpha subunit
  • Horse(100062186) sodium channel, voltage-gated, type VII, alpha subunit
  • cow(507516) sodium channel, voltage-gated, type VII, alpha subunit
  • sheep(101109522) sodium channel, voltage-gated, type VII, alpha subunit
  • domestic cat(101082080) sodium channel, voltage-gated, type VII, alpha subunit

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-SCN7A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-SCN7A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

Número de producto
Descripción
Especie
Lidocaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Lidocaine, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Lidocaine hydrochloride monohydrate, solid,
Especie
human
Procaine hydrochloride, ≥97%,
Especie
human
Lidocaine, United States Pharmacopeia (USP) Reference Standard,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Scn7a,
Especie
mouse