ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
Synonyms:
CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Species:
Human ITGAM (3684), Mouse Itgam (16409), Rat Itgam (25021), Horse ITGAM (100064803), dog ITGAM (489928), sheep ITGAM (443217), domestic guinea pig Itgam (100135561), domestic cat ITGAM (101087957), cow ITGAM (407124), naked mole-rat Itgam (101719288)
UniProtKB ID:
Gene ID:
- Human(3684) Summary: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- Mouse(16409) integrin alpha M
- Rat(25021) integrin, alpha M
- Horse(100064803) integrin, alpha M (complement component 3 receptor 3 subunit)
- dog(489928) integrin, alpha M (complement component 3 receptor 3 subunit)
- sheep(443217) integrin, alpha M (complement component 3 receptor 3 subunit)
- domestic guinea pig(100135561) integrin, alpha M (complement component 3 receptor 3 subunit)
- domestic cat(101087957) integrin, alpha M (complement component 3 receptor 3 subunit)
- cow(407124) integrin, alpha M (complement component 3 receptor 3 subunit)
- naked mole-rat(101719288) integrin, alpha M (complement component 3 receptor 3 subunit)
- Domestic Rabbit(100351865) integrin, alpha M (complement component 3 receptor 3 subunit)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD11b−FITC antibody produced in mouse, clone ICRF44, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD11b-FITC antibody produced in mouse, clone MEM-174, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Anti-CD11b (integrin alpha-M) antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM290, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
ANTI-CD11B(N-TERMINAL) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-ITGAM antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL1719, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot