ITGAV
integrin, alpha V
Synonyms:
CD51, MSK8, VNRA, VTNR
Species:
Human ITGAV (3685), Mouse Itgav (16410), Rat Itgav (296456), dog ITGAV (488437), naked mole-rat Itgav (101717672), domestic guinea pig Itgav (100728575), domestic cat ITGAV (101085820), chicken ITGAV (396420), Zebrafish itgav (100151255), Domestic Rabbit ITGAV (100008956) ...More
UniProtKB ID:
Gene ID:
- Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
- Mouse(16410) integrin alpha V
- Rat(296456) integrin, alpha V
- dog(488437) integrin, alpha V
- naked mole-rat(101717672) integrin, alpha V
- domestic guinea pig(100728575) integrin, alpha V
- domestic cat(101085820) integrin, alpha V
- chicken(396420) integrin, alpha V
- Zebrafish(100151255) integrin, alpha V
- Domestic Rabbit(100008956) integrin, alpha V
- cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
- sheep(443143) integrin, alpha V
- Horse(100068706) integrin, alpha V
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Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Integrin αv (Ab-1) Mouse mAb (272-17E6), liquid, clone 272-17E6, Calbiochem®,
Species Reactivity
human
Application
Monoclonal Anti-Integrin αV antibody produced in mouse, 1 mg/mL, clone P2W7, tissue culture supernatant,
Species Reactivity
human
Application
flow cytometry
Anti-Integrin alphaV Antibody, CT, Intracellular, serum, Chemicon®,
Species Reactivity
chicken, equine, goat, hamster, horse, human, mouse, pig, rat, sheep
Application
ELISA
immunohistochemistry
immunoprecipitation (IP)
radioimmunoassay
western blot
immunohistochemistry
immunoprecipitation (IP)
radioimmunoassay
western blot