NCF2
neutrophil cytosolic factor 2
Synonyms:
NCF-2, NOXA2, P67-PHOX, P67PHOX
Species:
Human NCF2 (4688), Mouse Ncf2 (17970), Rat Ncf2 (364018), naked mole-rat Ncf2 (101716459), Domestic Rabbit NCF2 (100008802), sheep NCF2 (101106094), Horse NCF2 (100051787), cow NCF2 (281346), dog NCF2 (480036), domestic cat NCF2 (101088712) ...More
UniProtKB ID:
Gene ID:
- Human(4688) Summary: This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]
- Mouse(17970) neutrophil cytosolic factor 2
- Rat(364018) neutrophil cytosolic factor 2
- naked mole-rat(101716459) neutrophil cytosolic factor 2
- Domestic Rabbit(100008802) neutrophil cytosolic factor 2
- sheep(101106094) neutrophil cytosolic factor 2
- Horse(100051787) neutrophil cytosolic factor 2
- cow(281346) neutrophil cytosolic factor 2
- dog(480036) neutrophil cytosolic factor 2
- domestic cat(101088712) neutrophil cytosolic factor 2
- Zebrafish(562473) neutrophil cytosolic factor 2
- domestic guinea pig(100733153) neutrophil cytosolic factor 2
- chicken(424445) neutrophil cytosolic factor 2
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